CPE antibody (AA 128-473) (HRP)

Catalog No. ABIN7974871

The Rabbit Polyclonal anti-CPE antibody is suitable to detect CPE in samples from Human, Mouse and Rat. It has been validated for WB, ELISA and IHC.

Quick Overview for CPE antibody (AA 128-473) (HRP) (ABIN7974871)

Target: CPE (Carboxypeptidase E (CPE))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CPE antibody is conjugated to HRP

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Product Details anti-CPE Antibody (HRP)

Binding Specificity: AA 128-473

Purpose: Anti-Carboxypeptidase E/CPE Antibody HRP Conjugated

Cross-Reactivity (Details): No cross-reactivity with other proteins

Purification: Immunogen affinity purified.

Immunogen: E.coli-derived human CPE recombinant protein (Position: 128-473).

Isotype: IgG

Application Details

Application Notes: Western blot, Optimal dilutions should be determined by end users. Immunohistochemistry (Paraffin-embedded Section), Optimal dilutions should be determined by end users. ELISA, Optimal dilutions should be determined by end users.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4.

Storage: -20 °C

Storage Comment: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing.

Expiry Date: 12 months

Target Details for CPE

Target: CPE (Carboxypeptidase E (CPE))

Alternative Name: CPE

Background:

Background: This gene encodes a member of the M14 family of metallocarboxypeptidases. The encoded preproprotein is proteolytically processed to generate the mature peptidase. This peripheral membrane protein cleaves C-terminal amino acid residues and is involved in the biosynthesis of peptide hormones and neurotransmitters, including insulin. This protein may also function independently of its peptidase activity, as a neurotrophic factor that promotes neuronal survival, and as a sorting receptor that binds to regulated secretory pathway proteins, including prohormones. Mutations in this gene are implicated in type 2 diabetes.

Gene Full Name: carboxypeptidase E

Gene ID: 1363

UniProt: P16870

Pathways: Peptide Hormone Metabolism, Synaptic Membrane