CEACAM1 antibody (AA 34-382) (Fluoro488)

Catalog No. ABIN7974922

The Rabbit Polyclonal anti-CEACAM1 antibody is suitable to detect CEACAM1 in samples from Rat and Mouse. It has been validated for FACS.

Quick Overview for CEACAM1 antibody (AA 34-382) (Fluoro488) (ABIN7974922)

Target: CEACAM1 (Carcinoembryonic Antigen-Related Cell Adhesion Molecule 1 (CEACAM1))

Reactivity: Rat, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CEACAM1 antibody is conjugated to Fluoro488

Application: Flow Cytometry (FACS)

Product Details anti-CEACAM1 Antibody (Fluoro488)

Binding Specificity: AA 34-382

Purpose: Anti-Ceacam1 Antibody Fluoro488 Conjugated

Predicted Reactivity: Mouse Ceacam1 shares 55.5%,68.8% amino acid (aa) sequence identity with human,rat Ceacam1,respectively.

Purification: Immunogen affinity purified.

Immunogen: E.coli-derived mouse Ceacam1 recombinant protein (Position: A34-D382). Mouse Ceacam1 shares 55.5% and 68.8% amino acid (aa) sequence identity with human and rat Ceacam1, respectively.

Isotype: IgG

Application Details

Application Notes: Flow Cytometry, Optimal dilutions should be determined by end users.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

Expiry Date: 12 months

Target Details for CEACAM1

Target: CEACAM1 (Carcinoembryonic Antigen-Related Cell Adhesion Molecule 1 (CEACAM1))

Alternative Name: Ceacam1

Background:

Background: Carcinoembryonic antigen-related cell adhesion molecule 1 (biliary glycoprotein) (CEACAM1) also known as CD66a (Cluster of Differentiation 66a), is a human glycoprotein, and a member of the carcinoembryonic antigen (CEA) gene family. CEACAM1 (carcinoembryonic antigen-related cell adhesion molecule 1) is thought to be a member of the immunoglobulin superfamily and is known as an epithelial tumor suppressor and an angiogenic growth factor. It has also been linked to the actin-based cytoskeleton. CEACAM1 is also known as a cellular receptor for a number of human mucosa pathogenic bacteria. The loss of activity of CEACAM1 has been related to the development of colorectal cancer.

Gene Full Name: CEA cell adhesion molecule 1

Gene ID: 26365

UniProt: P31809