IL10RB antibody (PE-Cy7)

Catalog No. ABIN747861

This anti-IL10RB antibody is a Rabbit Polyclonal antibody detecting IL10RB in WB and FACS. Suitable for Human, Mouse, Rat, Cow, Dog and Pig.

Quick Overview for IL10RB antibody (PE-Cy7) (ABIN747861)

Target: IL10RB (Interleukin 10 Receptor, beta (IL10RB))

Reactivity: Human, Mouse, Rat, Cow, Dog, Pig

Host: Rabbit

Clonality: Polyclonal

Conjugate: This IL10RB antibody is conjugated to PE-Cy7

Application: Western Blotting (WB), Flow Cytometry (FACS)

Product Details anti-IL10RB Antibody (PE-Cy7)

Cross-Reactivity: Human, Mouse, Rat

Predicted Reactivity: Dog,Cow,Pig,Horse,Rabbit

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human IL10RB

Isotype: IgG

Application Details

Application Notes: FCM(1:100-500)
Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Expiry Date: 12 months

Target Details for IL10RB

Target: IL10RB (Interleukin 10 Receptor, beta (IL10RB))

Alternative Name: IL-10RB/CRFB4

Background:

Synonyms: Interleukin-10 receptor subunit beta, IL-10 receptor subunit beta, IL-10R subunit beta, IL-10RB, Cytokine receptor class-II member 4, Cytokine receptor family 2 member 4, CRF2-4, Interleukin-10 receptor subunit 2, IL-10R subunit 2, IL-10R2, CDw210b, IL10RB, CRFB4, D21S58, D21S66

Background: Shared cell surface receptor required for the activation of five class 2 cytokines: IL10, IL22, IL26, IL28, and IFNL1. The IFNLR1/IL10RB dimer is a receptor for the cytokine ligands IFNL2 and IFNL3 and mediates their antiviral activity. The ligand/receptor complex stimulate the activation of the JAK/STAT signaling pathway leading to the expression of IFN-stimulated genes (ISG), which contribute to the antiviral state.

Molecular Weight: 39kDa

Gene ID: 3588

UniProt: Q08334