Cathepsin G antibody (AA 21-261) (Fluoro488)

Catalog No. ABIN7975901

The Fluoro488-conjugated Rabbit Polyclonal anti-Cathepsin G antibody (ABIN7975901) specifically detects Cathepsin G in FACS. The antibody is reactive with Mouse and Rat samples.

Quick Overview for Cathepsin G antibody (AA 21-261) (Fluoro488) (ABIN7975901)

Target: Cathepsin G (CTSG)

Reactivity: Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Cathepsin G antibody is conjugated to Fluoro488

Application: Flow Cytometry (FACS)

Product Details anti-Cathepsin G Antibody (Fluoro488)

Binding Specificity: AA 21-261

Purpose: Anti-Cathepsin G/CTSG Antibody Fluoro488 Conjugated

Specificity: No cross reactivity with other proteins.

Cross-Reactivity (Details): No cross-reactivity with other proteins.

Predicted Reactivity: Mouse Cathepsin G shares 70.2% amino acid (aa) sequence identity with human Cathepsin G.

Purification: Immunogen affinity purified.

Immunogen: E.coli-derived mouse Cathepsin G recombinant protein (Position: I21-T261). Mouse Cathepsin G shares 70.2% amino acid (aa) sequence identity with human Cathepsin G.

Isotype: IgG

Application Details

Application Notes: Flow Cytometry, Optimal dilutions should be determined by end users.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

Expiry Date: 12 months

Target Details for Cathepsin G

Target: Cathepsin G (CTSG)

Alternative Name: Ctsg

Background:

Background: Cathepsin G is an enzymatic protein belonging to the peptidase or protease families. In humans, it is coded by the CTSG?gene.?This gene is mapped to 14q12. In transgenic mice, it was found that?human Cathepsin G gene was expressed in early myeloid precursors in a manner coordinate with the expression of the endogenous murine gene in the bone marrow and spleen. The protein encoded by this?gene, a member of the?peptidase S1 protein family, is found in azurophil granules of neutrophilic polymorphonuclear?leukocytes.?The encoded protease has a specificity similar to that of?chymotrypsin C, and may participate in the killing and digestion of engulfed pathogens, and in?connective tissue?remodeling at sites of?inflammation.?

Gene Full Name: cathepsin G

Gene ID: 13035

UniProt: P28293

Pathways: ACE Inhibitor Pathway, Peptide Hormone Metabolism, Regulation of Systemic Arterial Blood Pressure by Hormones