Cathepsin G antibody (AA 25-252) (HRP)

Catalog No. ABIN7975916

The HRP-conjugated Rabbit Polyclonal anti-Cathepsin G antibody (ABIN7975916) specifically detects Cathepsin G in WB, ELISA and IHC. The antibody is reactive with Human samples.

Quick Overview for Cathepsin G antibody (AA 25-252) (HRP) (ABIN7975916)

Target: Cathepsin G (CTSG)

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Cathepsin G antibody is conjugated to HRP

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Product Details anti-Cathepsin G Antibody (HRP)

Binding Specificity: AA 25-252

Purpose: Anti-Cathepsin G/CTSG Antibody HRP Conjugated

Specificity: No cross reactivity with other proteins.

Cross-Reactivity (Details): No cross-reactivity with other proteins

Predicted Reactivity: coli-derived human Cathepsin G recombinant protein (Position: R25-E252). Human Cathepsin G shares 69.7% amino acid (aa) sequence identity with mouse Cathepsin G.

Purification: Immunogen affinity purified.

Immunogen: E. coli-derived human Cathepsin G recombinant protein (Position: R25-E252). Human Cathepsin G shares 69.7% amino acid (aa) sequence identity with mouse Cathepsin G.

Isotype: IgG

Application Details

Application Notes: Western blot, Optimal dilutions should be determined by end users. Immunohistochemistry (Paraffin-embedded Section), Optimal dilutions should be determined by end users. ELISA, Optimal dilutions should be determined by end users.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4.

Storage: -20 °C

Storage Comment: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing.

Expiry Date: 12 months

Target Details for Cathepsin G

Target: Cathepsin G (CTSG)

Alternative Name: CTSG

Background:

Background: Cathepsin G is an enzymatic protein belonging to the peptidase or protease families. In humans, it is coded by the CTSG gene. This gene is mapped to 14q12. In transgenic mice, it was found that human Cathepsin G gene was expressed in early myeloid precursors in a manner coordinate with the expression of the endogenous murine gene in the bone marrow and spleen. The protein encoded by this gene, a member of the peptidase S1 protein family, is found in azurophil granules of neutrophilic polymorphonuclear leukocytes. The encoded protease has a specificity similar to that of chymotrypsin C, and may participate in the killing and digestion of engulfed pathogens, and in connective tissue remodeling at sites of inflammation.

Gene Full Name: cathepsin G

Gene ID: 1511

UniProt: P08311

Pathways: ACE Inhibitor Pathway, Peptide Hormone Metabolism, Regulation of Systemic Arterial Blood Pressure by Hormones