CD163 antibody (AA 122-1039) (Fluoro594)

Catalog No. ABIN7976266

The Rabbit Polyclonal anti-CD163 antibody is suitable to detect CD163 in samples from Mouse and Rat. It has been validated for FACS.

Quick Overview for CD163 antibody (AA 122-1039) (Fluoro594) (ABIN7976266)

Target: CD163

Reactivity: Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CD163 antibody is conjugated to Fluoro594

Application: Flow Cytometry (FACS)

Product Details anti-CD163 Antibody (Fluoro594)

Binding Specificity: AA 122-1039

Purpose: Anti-Cd163 Antibody Fluoro594 Conjugated

Cross-Reactivity (Details): No cross-reactivity with other proteins.

Purification: Immunogen affinity purified.

Immunogen: E.coli-derived mouse Cd163 recombinant protein (Position: N122-H1039).

Isotype: IgG

Application Details

Application Notes: Flow Cytometry, Optimal dilutions should be determined by end users.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

Expiry Date: 12 months

Target Details for CD163

Target: CD163

Alternative Name: Cd163

Background:

Background: CD163 (Cluster of Differentiation 163) is a protein that in humans is encoded by the CD163 gene. The protein encoded by this gene is a member of the scavenger receptor cysteine-rich (SRCR) superfamily, and is exclusively expressed in monocytes and macrophages. It functions as an acute phase-regulated receptor involved in the clearance and endocytosis of hemoglobin/haptoglobin complexes by macrophages, and may thereby protect tissues from free hemoglobin-mediated oxidative damage. This protein may also function as an innate immune sensor for bacteria and inducer of local inflammation. Alternatively spliced transcript variants encoding different isoforms have been described for this gene.

Gene Full Name: CD163 antigen

Gene ID: 93671

UniProt: Q2VLH6