CD63 antibody (AA 103-203) (Fluoro594)

Catalog No. ABIN7977256

The Rabbit Polyclonal anti-CD63 antibody is suitable to detect CD63 in samples from Mouse and Rat. It has been validated for FACS.

Quick Overview for CD63 antibody (AA 103-203) (Fluoro594) (ABIN7977256)

Target: CD63

Reactivity: Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CD63 antibody is conjugated to Fluoro594

Application: Flow Cytometry (FACS)

Product Details anti-CD63 Antibody (Fluoro594)

Binding Specificity: AA 103-203

Purpose: Anti-Cd63 Antibody Fluoro594 Conjugated

Cross-Reactivity (Details): No cross reactivity with other proteins.

Predicted Reactivity: Mouse Cd63 shares 67.3%,93.1% amino acid (aa) sequence identity with human,rat Cd63,respectively.

Purification: Immunogen affinity purified.

Immunogen: E.coli-derived mouse Cd63 recombinant protein (Position: A103-I203). Mouse Cd63 shares 67.3% and 93.1% amino acid (aa) sequence identity with human and rat Cd63, respectively.

Isotype: IgG

Application Details

Application Notes: Flow Cytometry, Optimal dilutions should be determined by end users.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

Expiry Date: 12 months

Target Details for CD63

Target: CD63

Alternative Name: Cd63

Background:

Background: CD63 antigen is a protein that, in humans, is encoded by the CD63 gene. The protein encoded by this gene is a member of the transmembrane 4 superfamily, also known as the tetraspanin family. Most of these members are cell-surface proteins that are characterized by the presence of four hydrophobic domains. The proteins mediate signal transduction events that play a role in the regulation of cell development, activation, growth and motility. The encoded protein is a cell surface glycoprotein that is known to complex with integrins. It may function as a blood platelet activation marker. Deficiency of this protein is associated with Hermansky-Pudlak syndrome. Also this gene has been associated with tumor progression. Alternative splicing results in multiple transcript variants encoding different protein isoforms.

Gene Full Name: CD63 antigen

Gene ID: 12512

UniProt: P41731