CENPH antibody (AA 37-247) (Biotin)

Catalog No. ABIN7978078

The Rabbit Polyclonal anti-CENPH antibody is suitable to detect CENPH in samples from Human. It has been validated for WB, ELISA and IHC.

Quick Overview for CENPH antibody (AA 37-247) (Biotin) (ABIN7978078)

Target: CENPH (Centromere Protein H (CENPH))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CENPH antibody is conjugated to Biotin

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Product Details anti-CENPH Antibody (Biotin)

Binding Specificity: AA 37-247

Purpose: Anti-CENPH Antibody Biotin Conjugated

Cross-Reactivity (Details): No cross-reactivity with other proteins.

Purification: Immunogen affinity purified.

Immunogen: E.coli-derived human CENPH recombinant protein (Position: E37-M247).

Isotype: IgG

Application Details

Application Notes: Western blot, Optimal dilutions should be determined by end users. Immunohistochemistry (Paraffin-embedded Section), Optimal dilutions should be determined by end users. ELISA, Optimal dilutions should be determined by end users.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing.

Expiry Date: 12 months

Target Details for CENPH

Target: CENPH (Centromere Protein H (CENPH))

Alternative Name: CENPH

Background:

Background: Centromere protein H is a protein that in humans is encoded by the CENPH gene. Centromere and kinetochore proteins play a critical role in centromere structure, kinetochore formation, and sister chromatid separation. The protein encoded by this gene colocalizes with inner kinetochore plate proteins CENP-A and CENP-C in both interphase and metaphase. It localizes outside of centromeric heterochromatin, where CENP-B is localized, and inside the kinetochore corona, where CENP-E is localized during prometaphase. It is thought that this protein can bind to itself, as well as to CENP-A, CENP-B or CENP-C. Multimers of the protein localize constitutively to the inner kinetochore plate and play an important role in the organization and function of the active centromere-kinetochore complex.

Gene Full Name: centromere protein H

Gene ID: 64946

UniProt: Q9H3R5