CCT2 antibody (AA 414-535) (PE)

Catalog No. ABIN7978251

This Rabbit Polyclonal antibody specifically detects CCT2 in FACS. It exhibits reactivity toward Human, Mouse and Rat.

Quick Overview for CCT2 antibody (AA 414-535) (PE) (ABIN7978251)

Target: CCT2 (Chaperonin Containing TCP1, Subunit 2 (Beta) (CCT2))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CCT2 antibody is conjugated to PE

Application: Flow Cytometry (FACS)

Product Details anti-CCT2 Antibody (PE)

Binding Specificity: AA 414-535

Purpose: Anti-TCP1 beta/CCT2 Antibody PE Conjugated

Specificity: No cross reactivity with other proteins.

Cross-Reactivity (Details): No cross-reactivity with other proteins

Predicted Reactivity: Human CCT2 shares 95.9%,93.4% amino acid (aa) sequence identity with mouse,rat CCT2,respectively.

Purification: Immunogen affinity purified.

Immunogen: E.coli-derived human CCT2 recombinant protein (Position: E414-C535). Human CCT2 shares 95.9% and 93.4% amino acid (aa) sequence identity with mouse and rat CCT2, respectively.

Isotype: IgG

Application Details

Application Notes: Flow Cytometry, Optimal dilutions should be determined by end users.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

Expiry Date: 12 months

Target Details for CCT2

Target: CCT2 (Chaperonin Containing TCP1, Subunit 2 (Beta) (CCT2))

Alternative Name: CCT2

Background:

Background: T-complex protein 1 subunit beta (TCP1 beta) is a protein that in humans is encoded by the CCT2 gene. The protein encoded by this gene is a molecular chaperone that is a member of the chaperonin containing TCP1 complex (CCT), also known as the TCP1 ring complex (TRiC). This complex consists of two identical stacked rings, each containing eight different proteins. Unfolded polypeptides enter the central cavity of the complex and are folded in an ATP-dependent manner. The complex folds various proteins, including actin and tubulin. Two transcript variants encoding different isoforms have been found for this gene.

Gene Full Name: chaperonin containing TCP1 subunit 2

Gene ID: 10576

UniProt: P78371