XCL1 antibody (AA 22-114) (Fluoro647)

Catalog No. ABIN7978396

The Rabbit Polyclonal anti-XCL1 antibody is suitable to detect XCL1 in samples from Human. It has been validated for FACS.

Quick Overview for XCL1 antibody (AA 22-114) (Fluoro647) (ABIN7978396)

Target: XCL1 (Chemokine (C Motif) Ligand 1 (XCL1))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This XCL1 antibody is conjugated to Fluoro647

Application: Flow Cytometry (FACS)

Product Details anti-XCL1 Antibody (Fluoro647)

Binding Specificity: AA 22-114

Purpose: Anti-Lymphotactin/XCL1 Antibody Fluoro647 Conjugated

Specificity: No cross reactivity with other proteins.

Cross-Reactivity (Details): No cross-reactivity with other proteins

Predicted Reactivity: Human Lymphotactin shares 60.2%,57% amino acid (aa) sequence identity with mouse,rat Lymphotactin,respectively.

Purification: Immunogen affinity purified.

Immunogen: E.coli-derived human Lymphotactin recombinant protein (Position: V22-G114). Human Lymphotactin shares 60.2% and 57% amino acid (aa) sequence identity with mouse and rat Lymphotactin, respectively.

Isotype: IgG

Application Details

Application Notes: Flow Cytometry, Optimal dilutions should be determined by end users.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

Expiry Date: 12 months

Target Details for XCL1

Target: XCL1 (Chemokine (C Motif) Ligand 1 (XCL1))

Alternative Name: XCL1

Background:

Background: Chemokine (C motif) ligand (XCL1) is a small cytokine belonging to the XC chemokine family that is also known as lymphotactin. Muller et al. (1995) mapped the gene to chromosome 1q23 by FISH. The sequence of the deduced 114-amino acid protein is most homologous to the CC chemokines CCL8 and CCL3. It is found in high levels in spleen, thymus, intestine and peripheral blood leukocytes, and at lower levels in lung, prostate gland and ovary. XCL1 induces the migration of cells expressing XCR1.

Gene Full Name: X-C motif chemokine ligand 1

Gene ID: 6375

UniProt: P47992

Pathways: Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response, Activated T Cell Proliferation