CXCL10 antibody (AA 22-98) (Fluoro647)

Catalog No. ABIN7979100

This Rabbit Polyclonal antibody specifically detects CXCL10 in FACS. It exhibits reactivity toward Human.

Quick Overview for CXCL10 antibody (AA 22-98) (Fluoro647) (ABIN7979100)

Target: CXCL10 (Chemokine (C-X-C Motif) Ligand 10 (CXCL10))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CXCL10 antibody is conjugated to Fluoro647

Application: Flow Cytometry (FACS)

Product Details anti-CXCL10 Antibody (Fluoro647)

Binding Specificity: AA 22-98

Purpose: Anti-IP10/CXCL10 Antibody Fluoro647 Conjugated

Specificity: No cross reactivity with other proteins.

Cross-Reactivity (Details): No cross-reactivity with other proteins

Predicted Reactivity: coli-derived human IP10 recombinant protein (Position: V22-P98). Human IP10 shares 70.1%,72.7% amino acid (aa) sequence identity with mouse,rat IP10,respectively.

Purification: Immunogen affinity purified.

Immunogen: E. coli-derived human IP10 recombinant protein (Position: V22-P98). Human IP10 shares 70.1% and 72.7% amino acid (aa) sequence identity with mouse and rat IP10, respectively.

Isotype: IgG

Application Details

Application Notes: Flow Cytometry, Optimal dilutions should be determined by end users.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

Expiry Date: 12 months

Target Details for CXCL10

Target: CXCL10 (Chemokine (C-X-C Motif) Ligand 10 (CXCL10))

Alternative Name: CXCL10

Background:

Background: C-X-C motif chemokine 10 (CXCL10), also known as Interferon gamma-induced protein 10 kDa (IP-10) or small-inducible cytokine B10, is a protein that in humans is encoded by the CXCL10 gene. It is a small cytokine belonging to the CXC chemokine family. The gene for CXCL10 is located on human chromosome 4 in a cluster among several other CXC chemokines. Luster et al. (1987) reported the isolation of an interferon-inducible gene that encodes a 98-amino acid protein called IP10. The chemokine IFN-gamma-inducible protein 10 (IP-10, CXCL10), a CXC chemokine, and its receptor, CXCR3, were found to be overexpressed in lymph node cells of EAMG rats. IP10 inhibits bone marrow colony formation, has antitumor activity in vivo, is a chemoattractant for human monocytes and T cells, and promotes T cell adhesion to endothelial cells.

Gene Full Name: C-X-C motif chemokine ligand 10

Gene ID: 3627

UniProt: P02778