CXCL2 antibody (AA 39-107) (PE)

Catalog No. ABIN7979209

The Rabbit Polyclonal anti-CXCL2 antibody is suitable to detect CXCL2 in samples from Human. It has been validated for FACS.

Quick Overview for CXCL2 antibody (AA 39-107) (PE) (ABIN7979209)

Target: CXCL2 (Chemokine (C-X-C Motif) Ligand 2 (CXCL2))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CXCL2 antibody is conjugated to PE

Application: Flow Cytometry (FACS)

Product Details anti-CXCL2 Antibody (PE)

Binding Specificity: AA 39-107

Purpose: Anti-CXCL2 Antibody PE Conjugated

Specificity: No cross reactivity with other proteins.

Cross-Reactivity (Details): No cross-reactivity with other proteins.

Predicted Reactivity: coli-derived human CXCL2 recombinant protein (Position: T39-N107). Human CXCL2 shares 66.7%,62.3% amino acid (aa) sequence identity with mouse,rat CXCL2,respectively.

Purification: Immunogen affinity purified.

Immunogen: E. coli-derived human CXCL2 recombinant protein (Position: T39-N107). Human CXCL2 shares 66.7% and 62.3% amino acid (aa) sequence identity with mouse and rat CXCL2, respectively.

Isotype: IgG

Application Details

Application Notes: Flow Cytometry, Optimal dilutions should be determined by end users.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

Expiry Date: 12 months

Target Details for CXCL2

Target: CXCL2 (Chemokine (C-X-C Motif) Ligand 2 (CXCL2))

Alternative Name: CXCL2

Background:

Background: Chemokine (C-X-C motif) ligand 2  (CXCL2) is a small cytokine belonging to the CXC chemokine family that is also called macrophage inflammatory protein 2-alpha  (MIP2-alpha), Growth-regulated protein beta  (Gro-beta) and Gro oncogene-2 (Gro-2). CXCL2 is 90% identical in amino acid sequence as a related chemokine, CXCL1. This chemokine is secreted by monocytes and macrophages and is chemotactic for polymorphonuclear leukocytes and hematopoietic stem cells. The gene for CXCL2 is located on human chromosome 4 in a cluster of other CXC chemokines. CXCL2 mobilizes cells by interacting with a cell surface chemokine receptor called CXCR2.

Gene Full Name: C-X-C motif chemokine ligand 2

Gene ID: 2920

UniProt: P19875

Pathways: Cellular Response to Molecule of Bacterial Origin