CXCL3 antibody (AA 32-100) (Fluoro550)

Catalog No. ABIN7979226

This Rabbit Polyclonal antibody specifically detects CXCL3 in FACS. It exhibits reactivity toward Mouse.

Quick Overview for CXCL3 antibody (AA 32-100) (Fluoro550) (ABIN7979226)

Target: CXCL3 (Chemokine (C-X-C Motif) Ligand 3 (CXCL3))

Reactivity: Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CXCL3 antibody is conjugated to Fluoro550

Application: Flow Cytometry (FACS)

Product Details anti-CXCL3 Antibody (Fluoro550)

Binding Specificity: AA 32-100

Purpose: Anti-GRO gamma/CXCL3 Antibody Fluoro550 Conjugated

Specificity: No cross reactivity with other proteins.

Cross-Reactivity (Details): No cross-reactivity with other proteins

Predicted Reactivity: coli-derived mouse GRO gamma recombinant protein (Position: S32-S100). Mouse GRO gamma shares 60.6%,90.6% amino acid (aa) sequence identity with human,rat GRO gamma,respectively.

Purification: Immunogen affinity purified.

Immunogen: E. coli-derived mouse GRO gamma recombinant protein (Position: S32-S100). Mouse GRO gamma shares 60.6% and 90.6% amino acid (aa) sequence identity with human and rat GRO gamma, respectively.

Isotype: IgG

Application Details

Application Notes: Flow Cytometry, Optimal dilutions should be determined by end users.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

Expiry Date: 12 months

Target Details for CXCL3

Target: CXCL3 (Chemokine (C-X-C Motif) Ligand 3 (CXCL3))

Alternative Name: CXCL3

Background:

Background: Chemokine (C-X-C motif) ligand 3 (CXCL3), also known as GRO protein gamma (GROg) and macrophage inflammatory protein-2-beta (MIP2b), is a small cytokine belonging to the CXC chemokine family. It is mapped to 14p2. CXCL3 controls migration and adhesion of monocytes and mediates its effects on its target cell by interacting with a cell surface chemokine receptor. It has been shown that CXCL3 regulates cell autonomously the migration of the precursors of cerebellar granule neurons toward the internal layers of cerebellum, during the morphogenesis of cerebellum. CXCL3 also play fundamental roles in the development, homeostasis and it has effects on cells of the central nervous system as well as on endothelial cells involved in angiogenesis or angiostasis.

Gene Full Name: C-X-C motif chemokine ligand 3

Gene ID: 330122

UniProt: Q6W5C0

Pathways: Cellular Response to Molecule of Bacterial Origin, Autophagy