CXCL5 antibody (AA 38-130) (Cy3)

Catalog No. ABIN7979235

This Rabbit Polyclonal antibody specifically detects CXCL5 in FACS. It exhibits reactivity toward Rat.

Quick Overview for CXCL5 antibody (AA 38-130) (Cy3) (ABIN7979235)

Target: CXCL5 (Chemokine (C-X-C Motif) Ligand 5 (CXCL5))

Reactivity: Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CXCL5 antibody is conjugated to Cy3

Application: Flow Cytometry (FACS)

Product Details anti-CXCL5 Antibody (Cy3)

Binding Specificity: AA 38-130

Purpose: Anti-CXCL5 Antibody Cy3 Conjugated

Specificity: No cross reactivity with other proteins.

Cross-Reactivity (Details): No cross-reactivity with other proteins.

Predicted Reactivity: coli-derived rat CXCL5 recombinant protein (Position: A38-Q130). Rat CXCL5 shares 58.7%,76.3% amino acid (aa) sequence identity with human,mouse CXCL5,respectively.

Purification: Immunogen affinity purified.

Immunogen: E. coli-derived rat CXCL5 recombinant protein (Position: A38-Q130). Rat CXCL5 shares 58.7% and 76.3% amino acid (aa) sequence identity with human and mouse CXCL5, respectively.

Isotype: IgG

Application Details

Application Notes: Flow Cytometry, 1-3 μg/1x10⁶ cells

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

Expiry Date: 12 months

Target Details for CXCL5

Target: CXCL5 (Chemokine (C-X-C Motif) Ligand 5 (CXCL5))

Alternative Name: Cxcl5

Background:

Background: C-X-C motif chemokine 5?or ENA-78 is a?protein?that in humans is encoded by the?CXCL5?gene. The protein encoded by this gene, CXCL5 is a small?cytokine?belonging to the CXC?chemokine?family. It is produced following stimulation of cells with the inflammatory cytokines?interleukin-1?or?tumor necrosis factor-alpha.?Expression of CXCL5 has also been observed ineosinophils, and can be inhibited with the type II?interferon?IFN-γ. This chemokine stimulates the chemotaxis of neutrophils possessing?angiogenic?properties. It elicits these effects by interacting with the cell surface?chemokine receptor?CXCR2.?The?gene?for CXCL5 is encoded on four?exons?and is located on human?chromosome 4?amongst several other CXC chemokine genes.?CXCL5 has been implicated in connective tissue remodelling.?Also, CXCL5 has been described to regulate neutrophil homeostasis.

Gene Full Name: C-X-C motif chemokine ligand 6

Gene ID: 105988538

UniProt: P97885

Pathways: Cellular Response to Molecule of Bacterial Origin, Regulation of Leukocyte Mediated Immunity