CXCR6 antibody (C-Term)

Catalog No. ABIN7979431

The Rabbit Polyclonal anti-CXCR6 antibody is suitable to detect CXCR6 in samples from Human. It has been validated for WB and IHC.

Quick Overview for CXCR6 antibody (C-Term) (ABIN7979431)

Target: CXCR6 (Chemokine (C-X-C Motif) Receptor 6 (CXCR6))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CXCR6 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Grade: Carrier-free

Product Details anti-CXCR6 Antibody

Binding Specificity: C-Term

Purpose: Anti-Bonzo/CXCR6 Antibody

Specificity: No cross reactivity with other proteins.

Cross-Reactivity (Details): No cross-reactivity with other proteins

Predicted Reactivity: different from the related mouse,rat sequences by three amino acids.

Characteristics: Anti-Bonzo/CXCR6 Antibody. Tested in IHC, WB applications. This antibody reacts with Human.

Purification: Immunogen affinity purified.

Immunogen: A synthetic peptide corresponding to a sequence at the C-terminus of human Bonzo, different from the related mouse and rat sequences by three amino acids.

Isotype: IgG

Application Details

Application Notes: Immunohistochemistry (Paraffin-embedded Section), 0.5-1 μg/mL, HumanWestern blot, 0.1-0.5 μg/mL, Human

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Concentration: 500 μg/mL

Buffer: Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.

Expiry Date: 12 months

Target Details for CXCR6

Target: CXCR6 (Chemokine (C-X-C Motif) Receptor 6 (CXCR6))

Alternative Name: CXCR6

Background:

Background: CXCR6 (Chemokine,CXC Motif, Receptor 6), also known as STRL33, is a protein that in humans is encoded by the CXCR6 gene. By Southern blot analysis of genomic DNA and somatic cell hybrid analysis, Liao et al. (1997) mapped the single-copy STRL33 gene to chromosome 3. Matloubian et al. (2000) found that human and mouse cells expressing CXCR6 showed a strong chemotactic response to CXCL16 but not to other chemokines. The authors concluded that CXCL16 and CXCR6 probably function in interactions between dendritic cells and T cells and in regulating T-cell migration in the splenic red pulp. Kim et al. (2001) concluded that CXCR6 may be important in the trafficking of effector T cells mediating type-1 inflammation.

Gene Full Name: C-X-C motif chemokine receptor 6

Sequence Similarities: Belongs to the G-protein coupled receptor 1 family.

Molecular Weight: 39 kDa

Gene ID: 10663

UniProt: O00574