CCBP2 antibody (AA 138-384)

Catalog No. ABIN7979497

The Rabbit Polyclonal anti-CCBP2 antibody is suitable to detect CCBP2 in samples from Human. It has been validated for WB, ELISA and IHC.

Quick Overview for CCBP2 antibody (AA 138-384) (ABIN7979497)

Target: CCBP2 (Chemokine Binding Protein 2 (CCBP2))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CCBP2 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Grade: Carrier-free

Product Details anti-CCBP2 Antibody

Binding Specificity: AA 138-384

Purpose: Anti-D6/ACKR2 Antibody

Specificity: No cross reactivity with other proteins.

Cross-Reactivity (Details): No cross-reactivity with other proteins.

Characteristics: Anti-D6/ACKR2 Antibody. Tested in ELISA, IHC, WB applications. This antibody reacts with Human.

Purification: Immunogen affinity purified.

Immunogen: E.coli-derived human D6/ACKR2 recombinant protein (Position: M138-A384).

Isotype: IgG

Application Details

Application Notes: Western blot, 0.1-0.5 μg/mL Immunohistochemistry (Paraffin-embedded Section), 0.5-1 μg/mL ELISA, 0.1-0.5 μg/mL

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Concentration: 500 μg/mL

Buffer: Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.

Expiry Date: 12 months

Target Details for CCBP2

Target: CCBP2 (Chemokine Binding Protein 2 (CCBP2))

Alternative Name: ACKR2

Background:

Background: This gene encodes a beta chemokine receptor, which is predicted to be a seven transmembrane protein similar to G protein-coupled receptors. Chemokines and their receptor-mediated signal transduction are critical for the recruitment of effector immune cells to the inflammation site. This gene is expressed in a range of tissues and hemopoietic cells. The expression of this receptor in lymphatic endothelial cells and overexpression in vascular tumors suggested its function in chemokine-driven recirculation of leukocytes and possible chemokine effects on the development and growth of vascular tumors. This receptor appears to bind the majority of beta-chemokine family members, however, its specific function remains unknown. This gene is mapped to chromosome 3p21.3, a region that includes a cluster of chemokine receptor genes.

Gene Full Name: atypical chemokine receptor 2

Molecular Weight: 55 kDa

Gene ID: 1238

UniProt: O00590