CETP antibody (C-Term) (Biotin)

Catalog No. ABIN7979586

This Rabbit Polyclonal antibody specifically detects CETP in WB, IHC and ELISA. It exhibits reactivity toward Human.

Quick Overview for CETP antibody (C-Term) (Biotin) (ABIN7979586)

Target: CETP (Cholesteryl Ester Transfer Protein (CETP))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CETP antibody is conjugated to Biotin

Application: Western Blotting (WB), Immunohistochemistry (IHC), ELISA

Product Details anti-CETP Antibody (Biotin)

Binding Specificity: C-Term

Purpose: Anti-CETP Antibody Biotin Conjugated

Specificity: No cross reactivity with other proteins.

Cross-Reactivity (Details): No cross-reactivity with other proteins

Purification: Immunogen affinity purified.

Immunogen: A synthetic peptide corresponding to a sequence at the C-terminus of human CETP.

Isotype: IgG

Application Details

Application Notes: Western blot, Optimal dilutions should be determined by end users. Immunohistochemistry (Paraffin-embedded Section), Optimal dilutions should be determined by end users. ELISA, Optimal dilutions should be determined by end users.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing.

Expiry Date: 12 months

Target Details for CETP

Target: CETP (Cholesteryl Ester Transfer Protein (CETP))

Alternative Name: CETP

Background:

Background: CETP (Cholesteryl Ester Transfer Protein Plasma), is a plasma protein that facilitates the transport of cholesteryl esters and triglycerides between the lipoproteins. CETP is also known as lipid transfer protein I (Day et al., 1994). Sparkes et al. (1987) used a CETP probe against DNA from a human/mouse somatic cell hybrid panel to assign the CETP gene to chromosome 16. Because the role of CETP in atherosclerosis remained unclear, Okamoto et al. (2000) attempted to develop a potent, specific CETP inhibitor. One inhibitor, JTT-705, forms a disulfide bond with CETP and increases high density lipoprotein (HDL) cholesterol, decreases non-HDL cholesterol, and inhibits the progression of atherosclerosis in rabbits.

Gene Full Name: cholesteryl ester transfer protein

Sequence Similarities: Belongs to the BPI/LBP/Plunc superfamily. BPI/LBP family.

Gene ID: 1071

UniProt: P11597