CETP antibody (C-Term)

Catalog No. ABIN7979596

The Rabbit Polyclonal anti-CETP antibody is suitable to detect CETP in samples from Human. It has been validated for WB.

Quick Overview for CETP antibody (C-Term) (ABIN7979596)

Target: CETP (Cholesteryl Ester Transfer Protein (CETP))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CETP antibody is un-conjugated

Application: Western Blotting (WB)

Grade: Carrier-free

Product Details anti-CETP Antibody

Binding Specificity: C-Term

Purpose: Anti-CETP Antibody

Specificity: No cross reactivity with other proteins.

Cross-Reactivity (Details): No cross-reactivity with other proteins

Characteristics: Anti-CETP Antibody. Tested in WB applications. This antibody reacts with Human.

Purification: Immunogen affinity purified.

Immunogen: A synthetic peptide corresponding to a sequence at the C-terminus of human CETP.

Isotype: IgG

Application Details

Application Notes: Western blot, 0.1-0.5 μg/mL, Human

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Concentration: 500 μg/mL

Buffer: Each vial contains antibody formulated with stabilizing components, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Thimerosal, 0.05 mg Sodium azide.

Preservative: Sodium azide, Thimerosal (Merthiolate)

Precaution of Use: This product contains Thimerosal (Merthiolate) and Sodium azide: POISONOUS AND HAZARDOUS SUBSTANCES which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.

Expiry Date: 12 months

Target Details for CETP

Target: CETP (Cholesteryl Ester Transfer Protein (CETP))

Alternative Name: CETP

Background:

Background: CETP (Cholesteryl Ester Transfer Protein Plasma), is a plasma protein that facilitates the transport of cholesteryl esters and triglycerides between the lipoproteins. CETP is also known as lipid transfer protein I (Day et al., 1994). Sparkes et al. (1987) used a CETP probe against DNA from a human/mouse somatic cell hybrid panel to assign the CETP gene to chromosome 16. Because the role of CETP in atherosclerosis remained unclear, Okamoto et al. (2000) attempted to develop a potent, specific CETP inhibitor. One inhibitor, JTT-705, forms a disulfide bond with CETP and increases high density lipoprotein (HDL) cholesterol, decreases non-HDL cholesterol, and inhibits the progression of atherosclerosis in rabbits.

Gene Full Name: cholesteryl ester transfer protein

Sequence Similarities: Belongs to the BPI/LBP/Plunc superfamily. BPI/LBP family.

Molecular Weight: 22 kDa

Gene ID: 1071

UniProt: P11597