Claudin 1 antibody (AA 96-211) (APC)

Catalog No. ABIN7980375

This Rabbit Polyclonal antibody specifically detects Claudin 1 in FACS. It exhibits reactivity toward Human.

Quick Overview for Claudin 1 antibody (AA 96-211) (APC) (ABIN7980375)

Target: Claudin 1 (CLDN1)

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Claudin 1 antibody is conjugated to APC

Application: Flow Cytometry (FACS)

Product Details anti-Claudin 1 Antibody (APC)

Binding Specificity: AA 96-211

Purpose: Anti-Claudin 1/CLDN1 Antibody APC Conjugated

Cross-Reactivity (Details): No cross-reactivity with other proteins.

Purification: Immunogen affinity purified.

Immunogen: E.coli-derived human Claudin 1/CLDN1 recombinant protein (Position: F96-V211).

Isotype: IgG

Application Details

Application Notes: Flow Cytometry, Optimal dilutions should be determined by end users.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

Expiry Date: 12 months

Target Details for Claudin 1

Target: Claudin 1 (CLDN1)

Alternative Name: CLDN1

Background:

Background: Claudin-1 is a protein that in humans is encoded by the CLDN1 gene. Tight junctions represent one mode of cell-to-cell adhesion in epithelial or endothelial cell sheets, forming continuous seals around cells and serving as a physical barrier to prevent solutes and water from passing freely through the paracellular space. These junctions are comprised of sets of continuous networking strands in the outwardly facing cytoplasmic leaflet, with complementary grooves in the inwardly facing extracytoplasmic leaflet. The protein encoded by this gene, a member of the claudin family, is an integral membrane protein and a component of tight junction strands. Loss of function mutations result in neonatal ichthyosis-sclerosing cholangitis syndrome.

Gene Full Name: claudin 1

Gene ID: 9076

UniProt: O95832

Pathways: Cell-Cell Junction Organization, Hepatitis C