Claudin 3 antibody (AA 101-220) (Fluoro550)

Catalog No. ABIN7980470

The Fluoro550-conjugated Rabbit Polyclonal anti-Claudin 3 antibody (ABIN7980470) specifically detects Claudin 3 in FACS. The antibody is reactive with Human samples.

Quick Overview for Claudin 3 antibody (AA 101-220) (Fluoro550) (ABIN7980470)

Target: Claudin 3 (CLDN3)

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Claudin 3 antibody is conjugated to Fluoro550

Application: Flow Cytometry (FACS)

Product Details anti-Claudin 3 Antibody (Fluoro550)

Binding Specificity: AA 101-220

Purpose: Anti-Claudin 3/CLDN3 Antibody Fluoro550 Conjugated

Cross-Reactivity (Details): No cross-reactivity with other proteins.

Purification: Immunogen affinity purified.

Immunogen: E.coli-derived human Claudin 3/CLDN3 recombinant protein (Position: A101-V220).

Isotype: IgG

Application Details

Application Notes: Flow Cytometry, Optimal dilutions should be determined by end users.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

Expiry Date: 12 months

Target Details for Claudin 3

Target: Claudin 3 (CLDN3)

Alternative Name: CLDN3

Background:

Background: Claudin 3, also known as CLDN3, is a protein which in humans is encoded by the CLDN3 gene. Tight junctions represent one mode of cell-to-cell adhesion in epithelial or endothelial cell sheets, forming continuous seals around cells and serving as a physical barrier to prevent solutes and water from passing freely through the paracellular space. These junctions are comprised of sets of continuous networking strands in the outwardly facing cytoplasmic leaflet, with complementary grooves in the inwardly facing extracytoplasmic leaflet. The protein encoded by this intronless gene, a member of the claudin family, is an integral membrane protein and a component of tight junction strands. It is also a low-affinity receptor for Clostridium perfringens enterotoxin, and shares aa sequence similarity with a putative apoptosis-related protein found in rat.

Gene Full Name: claudin 3

Gene ID: 1365

UniProt: O15551

Pathways: Hepatitis C