Claudin 5 antibody (C-Term) (Fluoro594)

Catalog No. ABIN7980493

The Rabbit Polyclonal anti-Claudin 5 antibody is suitable to detect Claudin 5 in samples from Human and Rat. It has been validated for FACS.

Quick Overview for Claudin 5 antibody (C-Term) (Fluoro594) (ABIN7980493)

Target: Claudin 5 (CLDN5)

Reactivity: Human, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Claudin 5 antibody is conjugated to Fluoro594

Application: Flow Cytometry (FACS)

Product Details anti-Claudin 5 Antibody (Fluoro594)

Binding Specificity: C-Term

Purpose: Anti-Claudin 5/CLDN5 Antibody Fluoro594 Conjugated

Specificity: No cross reactivity with other proteins.

Cross-Reactivity (Details): No cross-reactivity with other proteins

Predicted Reactivity: different from the related mouse sequence by three amino acids,from the related rat sequence by four amino acids.

Purification: Immunogen affinity purified.

Immunogen: A synthetic peptide corresponding to a sequence at the C-terminus of human Claudin 5, different from the related mouse sequence by three amino acids and from the related rat sequence by four amino acids.

Isotype: IgG

Application Details

Application Notes: Flow Cytometry, Optimal dilutions should be determined by end users.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

Expiry Date: 12 months

Target Details for Claudin 5

Target: Claudin 5 (CLDN5)

Alternative Name: CLDN5

Background:

Background: Claudin-5 (CLDN5) also known as BEC1, is a protein that in humans is encoded by the CLDN5 gene. By use of yeast artificial chromosomes, Claudin-5 is localized between polymorphic markers D22S944 and D22S941 on chromosome 22q11, both of which are deleted in more than 80 % of VCFS patients. This gene encodes a member of the claudin family. Claudins are integral membrane proteins and components of tight junction strands. Tight junction strands serve as a physical barrier to prevent solutes and water from passing freely through the paracellular space between epithelial or endothelial cell sheets. What's more, it plays a major role in tight junction-specific obliteration of the intercellular space.

Gene Full Name: claudin 5

Gene ID: 7122

UniProt: O00501

Pathways: Hepatitis C