Claudin 5 antibody (C-Term) (Cy3)

Catalog No. ABIN7980501

This Rabbit Polyclonal antibody specifically detects Claudin 5 in FACS. It exhibits reactivity toward Human.

Quick Overview for Claudin 5 antibody (C-Term) (Cy3) (ABIN7980501)

Target: Claudin 5 (CLDN5)

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Claudin 5 antibody is conjugated to Cy3

Application: Flow Cytometry (FACS)

Product Details anti-Claudin 5 Antibody (Cy3)

Binding Specificity: C-Term

Purpose: Anti-Claudin 5/CLDN5 Antibody Cy3 Conjugated

Cross-Reactivity (Details): No cross-reactivity with other proteins.

Purification: Immunogen affinity purified.

Immunogen: A synthetic peptide corresponding to a sequence at the C-terminus of human Claudin 5/CLDN5, which shares 95% and 90% amino acid (aa) sequence identity with mouse and rat Claudin 5/CLDN5, respectively.

Isotype: IgG

Application Details

Application Notes: Flow Cytometry, 1-3 μg/1x10⁶ cells

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

Expiry Date: 12 months

Target Details for Claudin 5

Target: Claudin 5 (CLDN5)

Alternative Name: CLDN5

Background:

Background: Claudin-5 is a protein that in humans is encoded by the CLDN5 gene. This gene encodes a member of the claudin family. Claudins are integral membrane proteins and components of tight junction strands. Tight junction strands serve as a physical barrier to prevent solutes and water from passing freely through the paracellular space between epithelial or endothelial cell sheets. Mutations in this gene have been found in patients with velocardiofacial syndrome. Alternative splicing results in multiple transcript variants encoding distinct isoforms.

Gene Full Name: claudin 5

Gene ID: 7122

UniProt: O00501

Pathways: Hepatitis C