CLPX antibody (AA 337-574) (HRP)

Catalog No. ABIN7980616

The Mouse Monoclonal anti-CLPX antibody is suitable to detect CLPX in samples from Human. It has been validated for WB, IHC and ELISA.

Quick Overview for CLPX antibody (AA 337-574) (HRP) (ABIN7980616)

Target: CLPX (ClpX Caseinolytic Peptidase X (CLPX))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This CLPX antibody is conjugated to HRP

Application: Western Blotting (WB), Immunohistochemistry (IHC), ELISA

Clone: 11C11

Product Details anti-CLPX Antibody (HRP)

Binding Specificity: AA 337-574

Purpose: Anti-CLPX Antibody (monoclonal, 11C11) HRP Conjugated

Specificity: No cross reactivity with other proteins.

Cross-Reactivity (Details): No cross-reactivity with other proteins.

Purification: Immunogen affinity purified.

Immunogen: E. coli-derived human CLPX recombinant protein (Position: A337-E574).

Isotype: IgG2b

Application Details

Application Notes: Western blot, Optimal dilutions should be determined by end users. Immunohistochemistry (Paraffin-embedded Section), Optimal dilutions should be determined by end users. ELISA, Optimal dilutions should be determined by end users.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4.

Storage: -20 °C

Storage Comment: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing.

Expiry Date: 12 months

Target Details for CLPX

Target: CLPX (ClpX Caseinolytic Peptidase X (CLPX))

Alternative Name: CLPX

Background:

Background: ATP-dependent Clp protease ATP-binding subunit clpX-like, mitochondrial is an enzyme that in humans is encoded by the CLPX gene. This protein is a member of the family of AAA Proteins (AAA+ ATPase) and is to form the protein complex of Clp protease. The protein encoded by this gene is part of a protease found in mitochondria. This protease is ATP-dependent and targets specific proteins for degradation. The protease consists of two heptameric rings of the CLPP catalytic subunit sandwiched between two hexameric rings of the chaperone subunit encoded by this gene. Targeted proteins are unwound by this protein and then passed on to the CLPP subunit for degradation. Two transcript variants, one protein-coding and the other non-protein coding, have been found for this gene.

Gene Full Name: caseinolytic mitochondrial matrix peptidase chaperone subunit X

Gene ID: 10845

UniProt: O76031