COBRA1 antibody (AA 1-252) (Cy3)

Catalog No. ABIN7980842

The Cy3-conjugated Rabbit Polyclonal anti-COBRA1 antibody (ABIN7980842) specifically detects COBRA1 in FACS. The antibody is reactive with Human, Mouse and Rat samples.

Quick Overview for COBRA1 antibody (AA 1-252) (Cy3) (ABIN7980842)

Target: COBRA1 (Cofactor of BRCA1 (COBRA1))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This COBRA1 antibody is conjugated to Cy3

Application: Flow Cytometry (FACS)

Product Details anti-COBRA1 Antibody (Cy3)

Binding Specificity: AA 1-252

Purpose: Anti-COBRA1/NELFB Antibody Cy3 Conjugated

Specificity: No cross reactivity with other proteins.

Cross-Reactivity (Details): No cross-reactivity with other proteins.

Purification: Immunogen affinity purified.

Immunogen: E. coli-derived human COBRA1 recombinant protein (Position: M1-E252).

Isotype: IgG

Application Details

Application Notes: Flow Cytometry, 1-3 μg/1x10⁶ cells

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

Expiry Date: 12 months

Target Details for COBRA1

Target: COBRA1 (Cofactor of BRCA1 (COBRA1))

Alternative Name: NELFB

Background:

Background: Cofactor of BRCA1, also known as COBRA1, is a human gene that encodes NELF-B. NELF-B is a subunit of negative elongation factor (NELF), which also includes NELF-A (WHSC2), either NELF-C or NELF-D (TH1L), and NELF-E (RDBP). NELF acts with DRB sensitivity-inducing factor (DSIF), a heterodimer of SPT4 (SUPT4H1) and SPT5 (SUPT5H), to cause transcriptional pausing of RNA polymerase II. COBRA1 was initially identified in a yeast two-hybrid screen using the BRCT1 domain of BRCA1 as bait.

Gene Full Name: negative elongation factor complex member B

Gene ID: 25920

UniProt: Q8WX92