CHCHD10 antibody (AA 80-142) (Biotin)

Catalog No. ABIN7980963

This Rabbit Polyclonal antibody specifically detects CHCHD10 in WB, ELISA and IHC. It exhibits reactivity toward Human, Mouse, Monkey and Rat.

Quick Overview for CHCHD10 antibody (AA 80-142) (Biotin) (ABIN7980963)

Target: CHCHD10 (Coiled-Coil-Helix-Coiled-Coil-Helix Domain Containing 10 (CHCHD10))

Reactivity: Human, Mouse, Monkey, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CHCHD10 antibody is conjugated to Biotin

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Product Details anti-CHCHD10 Antibody (Biotin)

Binding Specificity: AA 80-142

Purpose: Anti-CHCHD10 Antibody Biotin Conjugated

Cross-Reactivity (Details): No cross-reactivity with other proteins.

Purification: Immunogen affinity purified.

Immunogen: E.coli-derived human CHCHD10 recombinant protein (Position: P80-P142).

Isotype: IgG

Application Details

Application Notes: Western blot, Optimal dilutions should be determined by end users. Immunohistochemistry (Paraffin-embedded Section), Optimal dilutions should be determined by end users. ELISA, Optimal dilutions should be determined by end users.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing.

Expiry Date: 12 months

Target Details for CHCHD10

Target: CHCHD10 (Coiled-Coil-Helix-Coiled-Coil-Helix Domain Containing 10 (CHCHD10))

Alternative Name: CHCHD10

Background:

Background: Coiled-coil-helix-coiled-coil-helix domain-containing protein 10, mitochondrial, also known as Protein N27C7-4 is a protein that in humans is encoded by the CHCHD10 gene. This gene encodes a mitochondrial protein that is enriched at cristae junctions in the intermembrane space. It may play a role in cristae morphology maintenance or oxidative phosphorylation. Mutations in this gene cause frontotemporal dementia and/or amyotrophic lateral sclerosis-2. Alternative splicing of this gene results in multiple transcript variants. Related pseudogenes have been identified on chromosomes 7 and 19.

Gene Full Name: coiled-coil-helix-coiled-coil-helix domain containing 10

Gene ID: 400916

UniProt: Q8WYQ3