G-CSF antibody (AA 38-207) (Fluoro488)

Catalog No. ABIN7981318

The Rabbit Polyclonal anti-G-CSF antibody is suitable to detect G-CSF in samples from Human. It has been validated for FACS.

Quick Overview for G-CSF antibody (AA 38-207) (Fluoro488) (ABIN7981318)

Target: G-CSF (CSF3) (Colony Stimulating Factor 3 (Granulocyte) (CSF3))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This G-CSF antibody is conjugated to Fluoro488

Application: Flow Cytometry (FACS)

Product Details anti-G-CSF Antibody (Fluoro488)

Binding Specificity: AA 38-207

Purpose: Anti-G-CSF/CSF3 Antibody Fluoro488 Conjugated

Specificity: No cross reactivity with other proteins.

Cross-Reactivity (Details): No cross-reactivity with other proteins

Predicted Reactivity: coli-derived human G-CSF recombinant protein (Position: S38-P207). Human G-CSF shares 76% amino acid (aa) sequence identity with mouse G-CSF.

Purification: Immunogen affinity purified.

Immunogen: E. coli-derived human G-CSF recombinant protein (Position: S38-P207). Human G-CSF shares 76% amino acid (aa) sequence identity with mouse G-CSF.

Isotype: IgG

Application Details

Application Notes: Flow Cytometry, Optimal dilutions should be determined by end users.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

Expiry Date: 12 months

Target Details for G-CSF

Target: G-CSF (CSF3) (Colony Stimulating Factor 3 (Granulocyte) (CSF3))

Alternative Name: CSF3

Background:

Background: Granulocyte-colony stimulating factor (G-CSF or GCSF), also known as colony-stimulating factor 3 (CSF 3), is a glycoprotein that stimulates the bone marrow to produce granulocytes and stem cells and release them into the bloodstream. Functionally, it is a cytokine and hormone, a type of colony-stimulating factor, and is produced by a number of different tissues. The pharmaceutical analogs of naturally occurring G-CSF are called filgrastim and lenograstim. G-CSF also stimulates the survival, proliferation, differentiation, and function of neutrophil precursors and mature neutrophils.

Gene Full Name: colony stimulating factor 3

Sequence Similarities: Belongs to the IL-6 superfamily.

Gene ID: 1440

UniProt: P09919

Pathways: Cellular Response to Molecule of Bacterial Origin, Regulation of Actin Filament Polymerization