Complement Factor H antibody (AA 136-447) (Fluoro550)

Catalog No. ABIN7981550

The Fluoro550-conjugated Rabbit Polyclonal anti-Complement Factor H antibody (ABIN7981550) specifically detects Complement Factor H in FACS. The antibody is reactive with Rat and Mouse samples.

Quick Overview for Complement Factor H antibody (AA 136-447) (Fluoro550) (ABIN7981550)

Target: Complement Factor H (CFH)

Reactivity: Rat, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Complement Factor H antibody is conjugated to Fluoro550

Application: Flow Cytometry (FACS)

Product Details anti-Complement Factor H Antibody (Fluoro550)

Binding Specificity: AA 136-447

Purpose: Anti-Factor H/Cfh Antibody Fluoro550 Conjugated

Cross-Reactivity (Details): No cross-reactivity with other proteins.

Purification: Immunogen affinity purified.

Immunogen: E.coli-derived mouse Factor H/Cfh recombinant protein (Position: N136-T447).

Isotype: IgG

Application Details

Application Notes: Flow Cytometry, Optimal dilutions should be determined by end users.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

Expiry Date: 12 months

Target Details for Complement Factor H

Target: Complement Factor H (CFH)

Alternative Name: Cfh

Background:

Background: Factor H is a member of the regulators of complement activation family and is a complement control protein. This gene is a member of the Regulator of Complement Activation (RCA) gene cluster and encodes a protein with twenty short consensus repeat (SCR) domains. This protein is secreted into the bloodstream and has an essential role in the regulation of complement activation, restricting this innate defense mechanism to microbial infections. Mutations in this gene have been associated with hemolytic-uremic syndrome (HUS) and chronic hypocomplementemic nephropathy. Alternate transcriptional splice variants, encoding different isoforms, have been characterized.

Gene Full Name: complement component factor h

Gene ID: 12628

UniProt: P06909

Pathways: Complement System, Cellular Response to Molecule of Bacterial Origin