CFP antibody (C-Term) (PE)

Catalog No. ABIN7981588

The Rabbit Polyclonal anti-CFP antibody is suitable to detect CFP in samples from Human, Mouse and Rat. It has been validated for FACS.

Quick Overview for CFP antibody (C-Term) (PE) (ABIN7981588)

Target: CFP (Complement Factor P (CFP))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CFP antibody is conjugated to PE

Application: Flow Cytometry (FACS)

Product Details anti-CFP Antibody (PE)

Binding Specificity: C-Term

Purpose: Anti-CFP Antibody PE Conjugated

Specificity: No cross reactivity with other proteins.

Cross-Reactivity (Details): No cross-reactivity with other proteins.

Purification: Immunogen affinity purified.

Immunogen: A synthetic peptide corresponding to a sequence at the C-terminus of human CFP, which shares 86.1% amino acid (aa) sequence identity with both mouse and rat CFP.

Isotype: IgG

Application Details

Application Notes: Flow Cytometry, Optimal dilutions should be determined by end users.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

Expiry Date: 12 months

Target Details for CFP

Target: CFP (Complement Factor P (CFP))

Alternative Name: CFP

Background:

Background: Properdin (factor P) is a plasma protein that is active in the alternative complement pathway of the innate immune system. It is mapped to Xp11.23. This protein binds to many microbial surfaces and apoptotic cells and stabilizes the C3- and C5-convertase enzyme complexes in a feedback loop that ultimately leads to formation of the membrane attack complex and lysis of the target cell. Mutations in this gene result in two forms of properdin deficiency, which results in high susceptibility to meningococcal infections. Multiple alternatively spliced variants, encoding the same protein, have been identified.

Gene Full Name: complement factor properdin

Gene ID: 5199

UniProt: P27918

Pathways: Complement System