CRY1 antibody (N-Term) (FITC)

Catalog No. ABIN7981871

The FITC-conjugated Rabbit Polyclonal anti-CRY1 antibody (ABIN7981871) specifically detects CRY1 in FACS. The antibody is reactive with Human, Mouse and Rat samples.

Quick Overview for CRY1 antibody (N-Term) (FITC) (ABIN7981871)

Target: CRY1 (Cryptochrome 1 (Photolyase-Like) (CRY1))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CRY1 antibody is conjugated to FITC

Application: Flow Cytometry (FACS)

Product Details anti-CRY1 Antibody (FITC)

Binding Specificity: N-Term

Purpose: Anti-Cryptochrome I/CRY1 Antibody FITC Conjugated

Specificity: No cross reactivity with other proteins.

Cross-Reactivity (Details): No cross-reactivity with other proteins

Predicted Reactivity: different from the related mouse sequence by seven amino acids,and from the related rat sequence by six amino acids.

Purification: Immunogen affinity purified.

Immunogen: A synthetic peptide corresponding to a sequence at the N-terminus of human Cryptochrome I, different from the related mouse sequence by seven amino acids, and from the related rat sequence by six amino acids.

Isotype: IgG

Application Details

Application Notes: Flow Cytometry, Optimal dilutions should be determined by end users.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

Expiry Date: 12 months

Target Details for CRY1

Target: CRY1 (Cryptochrome 1 (Photolyase-Like) (CRY1))

Alternative Name: CRY1

Background:

Background: This gene encodes a flavin adenine dinucleotide-binding protein that is a key component of the circadian core oscillator complex, which regulates the circadian clock. And this gene is upregulated by CLOCK/ARNTL heterodimers but then represses this upregulation in a feedback loop using PER/CRY heterodimers to interact with CLOCK/ARNTL. Polymorphisms in this gene have been associated with altered sleep patterns. The encoded protein is widely conserved across plants and animals. Loss of the related gene in mouse results in a shortened circadian cycle in complete darkness.

Gene Full Name: cryptochrome circadian regulator 1

Sequence Similarities: Belongs to the DNA photolyase class-1 family.

Gene ID: 1407

UniProt: Q16526

Pathways: Response to Water Deprivation, Proton Transport