CTH antibody (AA 181-398) (Fluoro594)

Catalog No. ABIN7982598

This Rabbit Polyclonal antibody specifically detects CTH in FACS. It exhibits reactivity toward Human, Mouse and Rat.

Quick Overview for CTH antibody (AA 181-398) (Fluoro594) (ABIN7982598)

Target: CTH (Cystathionase (Cystathionine gamma-Lyase) (CTH))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CTH antibody is conjugated to Fluoro594

Application: Flow Cytometry (FACS)

Product Details anti-CTH Antibody (Fluoro594)

Binding Specificity: AA 181-398

Purpose: Anti-Cystathionase/CTH Antibody Fluoro594 Conjugated

Specificity: No cross reactivity with other proteins.

Cross-Reactivity (Details): No cross-reactivity with other proteins

Predicted Reactivity: Human Cystathionase shares 85.8% amino acid (aa) sequence identity with both mouse,rat Cystathionase.

Purification: Immunogen affinity purified.

Immunogen: E.coli-derived human Cystathionase recombinant protein (Position: D181-H398). Human Cystathionase shares 85.8% amino acid (aa) sequence identity with both mouse and rat Cystathionase.

Isotype: IgG

Application Details

Application Notes: Flow Cytometry, Optimal dilutions should be determined by end users.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

Expiry Date: 12 months

Target Details for CTH

Target: CTH (Cystathionase (Cystathionine gamma-Lyase) (CTH))

Alternative Name: CTH

Background:

Background: Cystathionine gamma-lyase (or cystathionase) is an enzyme which breaks down cystathionine into cysteine and α-ketobutyrate. The International Radiation Hybrid Mapping Consortium mapped the CTH gene to chromosome 1. The CTH gene had earlier been assigned to chromosome 16 by study of somatic cell hybrids. It is demonstrated that hydrogen sulfide (H2S) is physiologically generated by CTH.

Gene Full Name: cystathionine gamma-lyase

Sequence Similarities: Belongs to the CTCF zinc-finger protein family.

Gene ID: 10664

UniProt: P32929

Pathways: ER-Nucleus Signaling, Warburg Effect