CST3 antibody (AA 31-146) (Cy3)

Catalog No. ABIN7982738

The Cy3-conjugated Mouse Monoclonal anti-CST3 antibody (Clone 4H8) (ABIN7982738) specifically detects CST3 in FACS. The antibody is reactive with Human samples.

Quick Overview for CST3 antibody (AA 31-146) (Cy3) (ABIN7982738)

Target: CST3 (Cystatin C (CST3))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This CST3 antibody is conjugated to Cy3

Application: Flow Cytometry (FACS)

Clone: 4H8

Product Details anti-CST3 Antibody (Cy3)

Binding Specificity: AA 31-146

Purpose: Anti-Cystatin C/CST3 Antibody (monoclonal, 4H8) Cy3 Conjugated

Specificity: No cross reactivity with other proteins.

Cross-Reactivity (Details): No cross-reactivity with other proteins.

Purification: Immunogen affinity purified.

Immunogen: E. coli-derived human Cystatin C recombinant protein (Position: K31-A146).

Isotype: IgG2a

Application Details

Application Notes: Flow Cytometry, 1-3 μg/1x10⁶ cells

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

Expiry Date: 12 months

Target Details for CST3

Target: CST3 (Cystatin C (CST3))

Alternative Name: CST3

Background:

Background: Cystatin C or cystatin 3, a protein encoded by the CST3 gene, is mainly used as a biomarker of kidney function. Recently, it has been studied for its role in predicting new-onset or deteriorating cardiovascular disease. It also seems to play a role in brain disorders involving amyloid, such as Alzheimer's disease. In humans, all cells with a nucleus (cell core containing the DNA) produce cystatin C as a chain of 120 amino acids. It is found in virtually all tissues and body fluids. It is a potent inhibitor of lysosomal proteinases (enzymes from a special subunit of the cell that break down proteins) and probably one of the most important extracellular inhibitors of cysteine proteases (it prevents the breakdown of proteins outside the cell by a specific type of protein degrading enzymes). Cystatin C belongs to the type 2 cystatin gene family.

Gene Full Name: cystatin C

Gene ID: 1471

UniProt: P01034