CST3 antibody (AA 31-146) (HRP)

Catalog No. ABIN7982743

The Mouse Monoclonal anti-CST3 antibody is suitable to detect CST3 in samples from Human. It has been validated for WB, ELISA and IHC.

Quick Overview for CST3 antibody (AA 31-146) (HRP) (ABIN7982743)

Target: CST3 (Cystatin C (CST3))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This CST3 antibody is conjugated to HRP

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Clone: 4H8

Product Details anti-CST3 Antibody (HRP)

Binding Specificity: AA 31-146

Purpose: Anti-Cystatin C/CST3 Antibody (monoclonal, 4H8) HRP Conjugated

Specificity: No cross reactivity with other proteins.

Cross-Reactivity (Details): No cross-reactivity with other proteins.

Purification: Immunogen affinity purified.

Immunogen: E. coli-derived human Cystatin C recombinant protein (Position: K31-A146).

Isotype: IgG2a

Application Details

Application Notes: Western blot, Optimal dilutions should be determined by end users. Immunohistochemistry (Paraffin-embedded Section), Optimal dilutions should be determined by end users. ELISA, Optimal dilutions should be determined by end users.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4.

Storage: -20 °C

Storage Comment: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing.

Expiry Date: 12 months

Target Details for CST3

Target: CST3 (Cystatin C (CST3))

Alternative Name: CST3

Background:

Background: Cystatin C or cystatin 3, a protein encoded by the CST3 gene, is mainly used as a biomarker of kidney function. Recently, it has been studied for its role in predicting new-onset or deteriorating cardiovascular disease. It also seems to play a role in brain disorders involving amyloid, such as Alzheimer's disease. In humans, all cells with a nucleus (cell core containing the DNA) produce cystatin C as a chain of 120 amino acids. It is found in virtually all tissues and body fluids. It is a potent inhibitor of lysosomal proteinases (enzymes from a special subunit of the cell that break down proteins) and probably one of the most important extracellular inhibitors of cysteine proteases (it prevents the breakdown of proteins outside the cell by a specific type of protein degrading enzymes). Cystatin C belongs to the type 2 cystatin gene family.

Gene Full Name: cystatin C

Gene ID: 1471

UniProt: P01034