CDA antibody (N-Term) (APC)

Catalog No. ABIN7982788

The Rabbit Polyclonal anti-CDA antibody is suitable to detect CDA in samples from Human, Mouse and Rat. It has been validated for FACS.

Quick Overview for CDA antibody (N-Term) (APC) (ABIN7982788)

Target: CDA (Cytidine Deaminase (CDA))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CDA antibody is conjugated to APC

Application: Flow Cytometry (FACS)

Product Details anti-CDA Antibody (APC)

Binding Specificity: N-Term

Purpose: Anti-CDA Antibody APC Conjugated

Specificity: No cross reactivity with other proteins.

Cross-Reactivity (Details): No cross-reactivity with other proteins.

Purification: Immunogen affinity purified.

Immunogen: A synthetic peptide corresponding to a sequence at the N-terminus of human CDA, which shares 63% amino acid (aa) sequence identity with both mouse and rat CDA.

Isotype: IgG

Application Details

Application Notes: Flow Cytometry, Optimal dilutions should be determined by end users.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

Expiry Date: 12 months

Target Details for CDA

Target: CDA (Cytidine Deaminase (CDA))

Alternative Name: CDA

Background:

Background: Cytidine deaminase is an enzyme that in humans is encoded by the CDA gene. This gene is mapped to 1p36.12. It encodes an enzyme involved in pyrimidine salvaging. The encoded protein forms a homotetramer that catalyzes the irreversible hydrolytic deamination of cytidine and deoxycytidine to uridine and deoxyuridine, respectively. It is one of several deaminases responsible for maintaining the cellular pyrimidine pool. Mutations in this gene are associated with decreased sensitivity to the cytosine nucleoside analogue cytosine arabinoside used in the treatment of certain childhood leukemias.

Gene Full Name: cytidine deaminase

Gene ID: 978

UniProt: P32320