LTB4R2 antibody (AA 25-120)

Catalog No. ABIN748643

Product Details anti-LTB4R2 Antibody

Target: LTB4R2 (Leukotriene B4 Receptor 2 (LTB4R2))

Binding Specificity: AA 25-120

Reactivity: Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This LTB4R2 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Flow Cytometry (FACS), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Cross-Reactivity: Mouse, Rat

Predicted Reactivity: Human,Dog,Cow,Pig,Guinea Pig

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human LTB4-R2

Isotype: IgG

Application Details

Application Notes: WB 1:300-5000
ELISA 1:500-1000
FCM 1:20-100
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Expiry Date: 12 months

References for anti-LTB4R2 antibody (ABIN748643)

Zinn, Sisignano, Kern, Pierre, Tunaru, Jordan, Suo, Treutlein, Angioni, Ferreiros, Leffler, DeBruin, Offermanns, Geisslinger, Scholich: "The leukotriene B4 receptors BLT1 and BLT2 form an antagonistic sensitizing system in peripheral sensory neurons." in: The Journal of biological chemistry, Vol. 292, Issue 15, pp. 6123-6134, (2017) (PubMed).

Target Details for LTB4R2

Target: LTB4R2 (Leukotriene B4 Receptor 2 (LTB4R2))

Alternative Name: LTB4-R2 (LTB4R2 Products)

Synonyms: LTB4R2 antibody, BLT2 antibody, BLTR2 antibody, JULF2 antibody, KPG_004 antibody, LTB4-R 2 antibody, LTB4-R2 antibody, NOP9 antibody, 5830462O07Rik antibody, LTB4-R-2 antibody, leukotriene B4 receptor 2 antibody, LTB4R2 antibody, Ltb4r2 antibody

Background:

Synonyms: BLT2, NOP9, BLTR2, JULF2, KPG_004, LTB4-R2, LTB4-R 2, Leukotriene B4 receptor 2, LTB4 receptor JULF2, Leukotriene B4 receptor BLT2, Seven transmembrane receptor BLTR2, LTB4R2, BLT2R

Background: Low-affinity receptor for leukotrienes including leukotriene B4. Mediates chemotaxis of granulocytes and macrophages. The response is mediated via G-proteins that activate a phosphatidylinositol-calcium second messenger system. The rank order of affinities for the leukotrienes is LTB4 > 12-epi-LTB4 > LTB5 > LTB3.

Gene ID: 56413

UniProt: Q9NPC1

Pathways: cAMP Metabolic Process