LTB4R2 antibody (AA 25-120)

Catalog No. ABIN748643

There is 1 publication for this product available. The Rabbit Polyclonal anti-LTB4R2 antibody is suitable to detect LTB4R2 in samples from Human. It has been validated for WB, FACS, IF (cc), IF (p), IHC (p) and IHC (fro).

Quick Overview for LTB4R2 antibody (AA 25-120) (ABIN748643)

Target: LTB4R2 (Leukotriene B4 Receptor 2 (LTB4R2))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This LTB4R2 antibody is un-conjugated

Application: Western Blotting (WB), Flow Cytometry (FACS), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Product Details anti-LTB4R2 Antibody

Binding Specificity: AA 25-120

Purpose: LTB4-R2 Polyclonal Antibody

Cross-Reactivity: Human

Predicted Reactivity: Mouse,Rat,Dog,Cow,Pig,GuineaPig

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human LTB4-R2

Isotype: IgG

Application Details

Application Notes: WB(1:300-5000),

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Shipped at 4C. Store at -20C for one year. Avoid repeated freeze/thaw cycles.

Expiry Date: 12 months

References for anti-LTB4R2 antibody (ABIN748643)

Zinn, Sisignano, Kern, Pierre, Tunaru, Jordan, Suo, Treutlein, Angioni, Ferreiros, Leffler, DeBruin, Offermanns, Geisslinger, Scholich: "The leukotriene B4 receptors BLT1 and BLT2 form an antagonistic sensitizing system in peripheral sensory neurons." in: The Journal of biological chemistry, Vol. 292, Issue 15, pp. 6123-6134, (2017) (PubMed).

Target Details for LTB4R2

Target: LTB4R2 (Leukotriene B4 Receptor 2 (LTB4R2))

Alternative Name: LTB4-R2

Background:

Synonyms: BLT2, NOP9, BLTR2, JULF2, KPG_004, LTB4-R2, LTB4-R 2, Leukotriene B4 receptor 2, LTB4 receptor JULF2, Leukotriene B4 receptor BLT2, Seven transmembrane receptor BLTR2, LTB4R2, BLT2R

Background: Low-affinity receptor for leukotrienes including leukotriene B4. Mediates chemotaxis of granulocytes and macrophages. The response is mediated via G-proteins that activate a phosphatidylinositol-calcium second messenger system. The rank order of affinities for the leukotrienes is LTB4 > 12-epi-LTB4 > LTB5 > LTB3.

Gene ID: 56413

UniProt: Q9NPC1

Pathways: cAMP Metabolic Process