D Amino Acid Oxidase antibody (AA 20-347) (PE)

Catalog No. ABIN7983682

The Rabbit Polyclonal anti-D Amino Acid Oxidase antibody is suitable to detect D Amino Acid Oxidase in samples from Human and Rat. It has been validated for FACS.

Quick Overview for D Amino Acid Oxidase antibody (AA 20-347) (PE) (ABIN7983682)

Target: D Amino Acid Oxidase (DAO) (D-Amino-Acid Oxidase (DAO))

Reactivity: Human, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This D Amino Acid Oxidase antibody is conjugated to PE

Application: Flow Cytometry (FACS)

Product Details anti-D Amino Acid Oxidase Antibody (PE)

Binding Specificity: AA 20-347

Purpose: Anti-DAO Antibody PE Conjugated

Cross-Reactivity (Details): No cross-reactivity with other proteins.

Purification: Immunogen affinity purified.

Immunogen: E.coli-derived human DAO recombinant protein (Position: H20-L347).

Isotype: IgG

Application Details

Application Notes: Flow Cytometry, Optimal dilutions should be determined by end users.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

Expiry Date: 12 months

Target Details for D Amino Acid Oxidase

Target: D Amino Acid Oxidase (DAO) (D-Amino-Acid Oxidase (DAO))

Alternative Name: DAO

Background:

Background: D-amino acid oxidase (DAAO, also OXDA, DAMOX) is an enzyme with the function on a molecular level to oxidize D-amino acids to the corresponding α-keto acids, producing ammonia and hydrogen peroxide. This gene encodes the peroxisomal enzyme D-amino acid oxidase. The enzyme is a flavoprotein which uses flavin adenine dinucleotide (FAD) as its prosthetic group. Its substrates include a wide variety of D-amino acids, but it is inactive on the naturally occurring L-amino acids. Its biological function is not known, it may act as a detoxifying agent which removes D-amino acids that accumulate during aging. In mice, it degrades D-serine, a co-agonist of the NMDA receptor. This gene may play a role in the pathophysiology of schizophrenia.

Gene Full Name: D-amino acid oxidase

Gene ID: 1610

UniProt: P14920