DAZAP1 antibody (AA 1-189) (Fluoro647)

Catalog No. ABIN7983796

The Rabbit Polyclonal anti-DAZAP1 antibody is suitable to detect DAZAP1 in samples from Human, Mouse and Rat. It has been validated for FACS.

Quick Overview for DAZAP1 antibody (AA 1-189) (Fluoro647) (ABIN7983796)

Target: DAZAP1 (DAZ Associated Protein 1 (DAZAP1))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This DAZAP1 antibody is conjugated to Fluoro647

Application: Flow Cytometry (FACS)

Product Details anti-DAZAP1 Antibody (Fluoro647)

Binding Specificity: AA 1-189

Purpose: Anti-DAZAP1 Antibody Fluoro647 Conjugated

Specificity: No cross reactivity with other proteins.

Cross-Reactivity (Details): No cross-reactivity with other proteins.

Purification: Immunogen affinity purified.

Immunogen: E.coli-derived human DAZAP1 recombinant protein (Position: M1-E189).

Isotype: IgG

Application Details

Application Notes: Flow Cytometry, Optimal dilutions should be determined by end users.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

Expiry Date: 12 months

Target Details for DAZAP1

Target: DAZAP1 (DAZ Associated Protein 1 (DAZAP1))

Alternative Name: DAZAP1

Background:

Background: DAZ-associated protein 1 is a protein that in humans is encoded by the DAZAP1 gene. It is mapped to19p13.3. In mammals, the Y chromosome s the development of the testes and plays an important role in spermatogenesis. A high percentage of infertile men have deletions that map to regions of the Y chromosome. The DAZ (deleted in azoospermia) gene cluster maps to the AZFc region of the Y chromosome and is deleted in many azoospermic and severely oligospermic men. It is thought that the DAZ gene cluster arose from the transposition, amplification, and pruning of the ancestral autosomal gene DAZL also involved in germ cell development and gametogenesis. This gene encodes a RNA-binding protein with two RNP motifs that was originally identified by its interaction with the infertility factors DAZ and DAZL. Two isoforms are encoded by transcript variants of this gene.

Gene Full Name: DAZ associated protein 1

Gene ID: 26528

UniProt: Q96EP5