DCAF6 antibody (AA 22-825) (HRP)

Catalog No. ABIN7983898

The Rabbit Polyclonal anti-DCAF6 antibody is suitable to detect DCAF6 in samples from Human and Mouse. It has been validated for ELISA, IHC and WB.

Quick Overview for DCAF6 antibody (AA 22-825) (HRP) (ABIN7983898)

Target: DCAF6 (DDB1 and CUL4 Associated Factor 6 (DCAF6))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This DCAF6 antibody is conjugated to HRP

Application: ELISA, Immunohistochemistry (IHC), Western Blotting (WB)

Product Details anti-DCAF6 Antibody (HRP)

Binding Specificity: AA 22-825

Purpose: Anti-DCAF6 Antibody HRP Conjugated

Cross-Reactivity (Details): No cross-reactivity with other proteins

Predicted Reactivity: Human DCAF6 shares 85.7% amino acid (aa) sequence identity with mouse DCAF6.

Purification: Immunogen affinity purified.

Immunogen: E.coli-derived human DCAF6 recombinant protein (Position: E22-S825). Human DCAF6 shares 85.7% amino acid (aa) sequence identity with mouse DCAF6.

Isotype: IgG

Application Details

Application Notes: Western blot, Optimal dilutions should be determined by end users. Immunohistochemistry (Paraffin-embedded Section), Optimal dilutions should be determined by end users. ELISA, Optimal dilutions should be determined by end users.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4.

Storage: -20 °C

Storage Comment: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing.

Expiry Date: 12 months

Target Details for DCAF6

Target: DCAF6 (DDB1 and CUL4 Associated Factor 6 (DCAF6))

Alternative Name: DCAF6

Background:

Background: The protein encoded by this gene is a ligand-dependent coactivator of nuclear receptors, including nuclear receptor subfamily 3 group C member 1 (NR3C1), glucocorticoid receptor (GR), and androgen receptor (AR). The encoded protein and DNA damage binding protein 2 (DDB2) may act as tumor promoters and tumor suppressors, respectively, by regulating the level of androgen receptor in prostate tissues. In addition, this protein can act with glucocorticoid receptor to promote human papillomavirus gene expression.

Gene Full Name: DDB1 and CUL4 associated factor 6

Gene ID: 55827

UniProt: Q58WW2