DDX1 antibody (AA 562-740) (PE)

Catalog No. ABIN7983992

The PE-conjugated Mouse Monoclonal anti-DDX1 antibody (Clone 3I10) (ABIN7983992) specifically detects DDX1 in FACS. The antibody is reactive with Human, Mouse and Rat samples.

Quick Overview for DDX1 antibody (AA 562-740) (PE) (ABIN7983992)

Target: DDX1 (DEAD (Asp-Glu-Ala-Asp) Box Polypeptide 1 (DDX1))

Reactivity: Human, Mouse, Rat

Host: Mouse

Clonality: Monoclonal

Conjugate: This DDX1 antibody is conjugated to PE

Application: Flow Cytometry (FACS)

Clone: 3I10

Product Details anti-DDX1 Antibody (PE)

Binding Specificity: AA 562-740

Purpose: Anti-DDX1 Antibody (monoclonal, 3I10) PE Conjugated

Cross-Reactivity (Details): No cross-reactivity with other proteins.

Purification: Immunogen affinity purified.

Immunogen: E.coli-derived human DDX1 recombinant protein (Position: K562-F740).

Isotype: IgG1

Application Details

Application Notes: Flow Cytometry, Optimal dilutions should be determined by end users.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

Expiry Date: 12 months

Target Details for DDX1

Target: DDX1 (DEAD (Asp-Glu-Ala-Asp) Box Polypeptide 1 (DDX1))

Alternative Name: DDX1

Background:

Background: ATP-dependent RNA helicase DDX1 is an enzyme that in humans is encoded by the DDX1 gene. It is mapped to 2p24.3. DEAD box proteins, characterized by the conserved motif Asp-Glu-Ala-Asp (DEAD), are putative RNA helicases. They are implicated in a number of cellular processes involving alteration of RNA secondary structure such as translation initiation, nuclear and mitochondrial splicing, and ribosome and spliceosome assembly. Based on their distribution patterns, some members of this family are believed to be involved in embryogenesis, spermatogenesis, and cellular growth and division. This gene encodes a DEAD box protein of unknown function. It shows high transcription levels in 2 retinoblastoma cell lines and in tissues of neuroectodermal origin.

Gene Full Name: DEAD-box helicase 1

Gene ID: 1653

UniProt: Q92499

Pathways: Ribonucleoprotein Complex Subunit Organization