DOCK4 antibody (AA 191-1837) (Fluoro647)

Catalog No. ABIN7984613

The Fluoro647-conjugated Rabbit Polyclonal anti-DOCK4 antibody (ABIN7984613) specifically detects DOCK4 in FACS. The antibody is reactive with Human and Rat samples.

Quick Overview for DOCK4 antibody (AA 191-1837) (Fluoro647) (ABIN7984613)

Target: DOCK4 (Dedicator of Cytokinesis 4 (DOCK4))

Reactivity: Human, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This DOCK4 antibody is conjugated to Fluoro647

Application: Flow Cytometry (FACS)

Product Details anti-DOCK4 Antibody (Fluoro647)

Binding Specificity: AA 191-1837

Purpose: Anti-DOCK4 Antibody Fluoro647 Conjugated

Cross-Reactivity (Details): No cross-reactivity with other proteins.

Purification: Immunogen affinity purified.

Immunogen: E.coli-derived human DOCK4 recombinant protein (Position: K191-I1837).

Isotype: IgG

Application Details

Application Notes: Flow Cytometry, Optimal dilutions should be determined by end users.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

Expiry Date: 12 months

Target Details for DOCK4

Target: DOCK4 (Dedicator of Cytokinesis 4 (DOCK4))

Alternative Name: DOCK4

Background:

Background: This gene is a member of the dedicator of cytokinesis (DOCK) family and encodes a protein with a DHR-1 (CZH-1) domain, a DHR-2 (CZH-2) domain and an SH3 domain. This membrane-associated, cytoplasmic protein functions as a guanine nucleotide exchange factor and is involved in regulation of adherens junctions between cells. Mutations in this gene have been associated with ovarian, prostate, glioma, and colorectal cancers. Alternatively spliced variants which encode different protein isoforms have been described, but only one has been fully characterized.

Gene Full Name: dedicator of cytokinesis 4

Gene ID: 9732

UniProt: Q8N1I0