DOCK4 antibody (AA 191-1837)

Catalog No. ABIN7984614

This Rabbit Polyclonal antibody specifically detects DOCK4 in WB, IHC, ELISA and FACS. It exhibits reactivity toward Human and Rat.

Quick Overview for DOCK4 antibody (AA 191-1837) (ABIN7984614)

Target: DOCK4 (Dedicator of Cytokinesis 4 (DOCK4))

Reactivity: Human, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This DOCK4 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Flow Cytometry (FACS)

Grade: Carrier-free

Product Details anti-DOCK4 Antibody

Binding Specificity: AA 191-1837

Purpose: Anti-DOCK4 Antibody

Cross-Reactivity (Details): No cross-reactivity with other proteins.

Characteristics: Anti-DOCK4 Antibody. Tested in ELISA, Flow Cytometry, IHC, WB applications. This antibody reacts with Human, Rat.

Purification: Immunogen affinity purified.

Immunogen: E.coli-derived human DOCK4 recombinant protein (Position: K191-I1837).

Isotype: IgG

Application Details

Application Notes: Western blot, 0.25-0.5 μg/mL, Human, Rat Immunohistochemistry(Paraffin-embedded Section), 2-5 μg/mL, Human Flow Cytometry (Fixed), 1-3 μg/1x10⁶ cells, Human ELISA, 0.1-0.5 μg/mL, -

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Concentration: 500 μg/mL

Buffer: Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.

Storage: 4 °C,-20 °C

Storage Comment: At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.

Expiry Date: 12 months

Target Details for DOCK4

Target: DOCK4 (Dedicator of Cytokinesis 4 (DOCK4))

Alternative Name: DOCK4

Background:

Background: This gene is a member of the dedicator of cytokinesis (DOCK) family and encodes a protein with a DHR-1 (CZH-1) domain, a DHR-2 (CZH-2) domain and an SH3 domain. This membrane-associated, cytoplasmic protein functions as a guanine nucleotide exchange factor and is involved in regulation of adherens junctions between cells. Mutations in this gene have been associated with ovarian, prostate, glioma, and colorectal cancers. Alternatively spliced variants which encode different protein isoforms have been described, but only one has been fully characterized.

Gene Full Name: dedicator of cytokinesis 4

Molecular Weight: 250 kDa

Gene ID: 9732

UniProt: Q8N1I0