Desmocollin 2 antibody (AA 29-683) (PE)

Catalog No. ABIN7984962

This Rabbit Polyclonal antibody specifically detects Desmocollin 2 in FACS. It exhibits reactivity toward Human, Mouse and Rat.

Quick Overview for Desmocollin 2 antibody (AA 29-683) (PE) (ABIN7984962)

Target: Desmocollin 2 (DSC2)

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Desmocollin 2 antibody is conjugated to PE

Application: Flow Cytometry (FACS)

Product Details anti-Desmocollin 2 Antibody (PE)

Binding Specificity: AA 29-683

Purpose: Anti-DSC2 Antibody PE Conjugated

Cross-Reactivity (Details): No cross-reactivity with other proteins

Purification: Immunogen affinity purified.

Immunogen: E.coli-derived human DSC2 recombinant protein (Position: S29-P683).

Isotype: IgG

Application Details

Application Notes: Flow Cytometry, Optimal dilutions should be determined by end users.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

Expiry Date: 12 months

Target Details for Desmocollin 2

Target: Desmocollin 2 (DSC2)

Alternative Name: DSC2

Background:

Background: This gene encodes a member of the desmocollin protein subfamily. Desmocollins, along with desmogleins, are cadherin-like transmembrane glycoproteins that are major components of the desmosome. Desmosomes are cell-cell junctions that help resist shearing forces and are found in high concentrations in cells subject to mechanical stress. This gene is found in a cluster with other desmocollin family members on chromosome 18. Mutations in this gene are associated with arrhythmogenic right ventricular dysplasia-11, and reduced protein expression has been described in several types of cancer. Alternative splicing results in multiple transcript variants.

Gene Full Name: desmocollin 2

Gene ID: 1824

UniProt: Q02487