Desmoplakin antibody (AA 69-2195) (HRP)

Catalog No. ABIN7985049

This Rabbit Polyclonal antibody specifically detects Desmoplakin in WB, IHC and ELISA. It exhibits reactivity toward Human.

Quick Overview for Desmoplakin antibody (AA 69-2195) (HRP) (ABIN7985049)

Target: Desmoplakin (DSP)

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Desmoplakin antibody is conjugated to HRP

Application: Western Blotting (WB), Immunohistochemistry (IHC), ELISA

Product Details anti-Desmoplakin Antibody (HRP)

Binding Specificity: AA 69-2195

Purpose: Anti-Desmoplakin/DSP Antibody HRP Conjugated

Cross-Reactivity (Details): No cross-reactivity with other proteins.

Purification: Immunogen affinity purified.

Immunogen: E.coli-derived human Desmoplakin/DSP recombinant protein (Position: N69-H2195).

Isotype: IgG

Application Details

Application Notes: Western blot, Optimal dilutions should be determined by end users. Immunohistochemistry (Paraffin-embedded Section), Optimal dilutions should be determined by end users. ELISA, Optimal dilutions should be determined by end users.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4.

Storage: -20 °C

Storage Comment: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing.

Expiry Date: 12 months

Target Details for Desmoplakin

Target: Desmoplakin (DSP)

Alternative Name: DSP

Background:

Background: Desmoplakin is a protein in humans that is encoded by the DSP gene. This gene encodes a protein that anchors intermediate filaments to desmosomal plaques and forms an obligate component of functional desmosomes. Mutations in this gene are the cause of several cardiomyopathies and keratodermas, including skin fragility-woolly hair syndrome. Alternative splicing results in multiple transcript variants.

Gene Full Name: desmoplakin

Gene ID: 1832

UniProt: P15924

Pathways: Cell-Cell Junction Organization