DLG5 antibody (AA 168-1863) (Biotin)

Catalog No. ABIN7985685

This Rabbit Polyclonal antibody specifically detects DLG5 in WB, ELISA and IHC. It exhibits reactivity toward Human.

Quick Overview for DLG5 antibody (AA 168-1863) (Biotin) (ABIN7985685)

Target: DLG5 (Discs, Large Homolog 5 (DLG5))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This DLG5 antibody is conjugated to Biotin

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Product Details anti-DLG5 Antibody (Biotin)

Binding Specificity: AA 168-1863

Purpose: Anti-DLG5 Antibody Biotin Conjugated

Cross-Reactivity (Details): No cross-reactivity with other proteins

Purification: Immunogen affinity purified.

Immunogen: E.coli-derived human DLG5 recombinant protein (Position: A168-Q1863).

Isotype: IgG

Application Details

Application Notes: Western blot, Optimal dilutions should be determined by end users. Immunohistochemistry (Paraffin-embedded Section), Optimal dilutions should be determined by end users. ELISA, Optimal dilutions should be determined by end users.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing.

Expiry Date: 12 months

Target Details for DLG5

Target: DLG5 (Discs, Large Homolog 5 (DLG5))

Alternative Name: DLG5

Background:

Background: This gene encodes a member of the family of discs large (DLG) homologs, a subset of the membrane-associated guanylate kinase (MAGUK) superfamily. The MAGUK proteins are composed of a catalytically inactive guanylate kinase domain, in addition to PDZ and SH3 domains, and are thought to function as scaffolding molecules at sites of cell-cell contact. The protein encoded by this gene localizes to the plasma membrane and cytoplasm, and interacts with components of adherens junctions and the cytoskeleton. It is proposed to function in the transmission of extracellular signals to the cytoskeleton and in the maintenance of epithelial cell structure. Alternative splice variants have been described but their biological nature has not been determined.

Gene Full Name: discs large MAGUK scaffold protein 5

Gene ID: 9231

UniProt: Q8TDM6