DVL2 antibody (AA 89-576) (HRP)

Catalog No. ABIN7985725

The Rabbit Polyclonal anti-DVL2 antibody is suitable to detect DVL2 in samples from Human, Mouse and Rat. It has been validated for WB, IHC and ELISA.

Quick Overview for DVL2 antibody (AA 89-576) (HRP) (ABIN7985725)

Target: DVL2 (Dishevelled, Dsh Homolog 2 (Drosophila) (DVL2))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This DVL2 antibody is conjugated to HRP

Application: Western Blotting (WB), Immunohistochemistry (IHC), ELISA

Product Details anti-DVL2 Antibody (HRP)

Binding Specificity: AA 89-576

Purpose: Anti-DVL2 Antibody HRP Conjugated

Predicted Reactivity: Human DVL2 shares 97.3% amino acid (aa) sequence identity with mouse DVL2.

Purification: Immunogen affinity purified.

Immunogen: E.coli-derived human DVL2 recombinant protein (Position: L89-Y576). Human DVL2 shares 97.3% amino acid (aa) sequence identity with mouse DVL2.

Isotype: IgG

Application Details

Application Notes: Western blot, Optimal dilutions should be determined by end users. Immunohistochemistry (Paraffin-embedded Section), Optimal dilutions should be determined by end users. ELISA, Optimal dilutions should be determined by end users.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4.

Storage: -20 °C

Storage Comment: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing.

Expiry Date: 12 months

Target Details for DVL2

Target: DVL2 (Dishevelled, Dsh Homolog 2 (Drosophila) (DVL2))

Alternative Name: DVL2

Background:

Background: Segment polarity protein dishevelled homolog DVL-2 is a protein that in humans is encoded by the DVL2 gene. This gene encodes a member of the dishevelled (dsh) protein family. The vertebrate dsh proteins have approximately 40 % amino acid sequence similarity with Drosophila dsh. This gene encodes a 90-kD protein that undergoes posttranslational phosphorylation to form a 95-kD cytoplasmic protein, which may play a role in the signal transduction pathway mediated by multiple Wnt proteins. The mechanisms of dishevelled function in Wnt signaling are likely to be conserved among metazoans.

Gene Full Name: dishevelled segment polarity protein 2

Gene ID: 132299

UniProt: O14641

Pathways: Tube Formation