DDOST antibody (AA 1-420) (PE)

Catalog No. ABIN7986193

The Rabbit Polyclonal anti-DDOST antibody is suitable to detect DDOST in samples from Human, Mouse and Rat. It has been validated for FACS.

Quick Overview for DDOST antibody (AA 1-420) (PE) (ABIN7986193)

Target: DDOST (Dolichyl-diphosphooligosaccharide--Protein Glycosyltransferase (DDOST))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This DDOST antibody is conjugated to PE

Application: Flow Cytometry (FACS)

Product Details anti-DDOST Antibody (PE)

Binding Specificity: AA 1-420

Purpose: Anti-DDOST Antibody PE Conjugated

Cross-Reactivity (Details): No cross-reactivity with other proteins

Purification: Immunogen affinity purified.

Immunogen: E.coli-derived human DDOST recombinant protein (Position: M1-R420).

Isotype: IgG

Application Details

Application Notes: Flow Cytometry, Optimal dilutions should be determined by end users.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

Expiry Date: 12 months

Target Details for DDOST

Target: DDOST (Dolichyl-diphosphooligosaccharide--Protein Glycosyltransferase (DDOST))

Alternative Name: DDOST

Background:

Background: This gene encodes a component of the oligosaccharyltransferase complex which catalyzes the transfer of high-mannose oligosaccharides to asparagine residues on nascent polypeptides in the lumen of the rough endoplasmic reticulum. The protein complex co-purifies with ribosomes. The product of this gene is also implicated in the processing of advanced glycation endproducts (AGEs), which form from non-enzymatic reactions between sugars and proteins or lipids and are associated with aging and hyperglycemia.

Gene Full Name: dolichyl-diphosphooligosaccharide--protein glycosyltransferase non-catalytic subunit

Gene ID: 1650

UniProt: P39656

Pathways: Cell RedoxHomeostasis