DCT antibody (AA 24-519) (Fluoro488)

Catalog No. ABIN7986209

The Fluoro488-conjugated Rabbit Polyclonal anti-DCT antibody (ABIN7986209) specifically detects DCT in FACS. The antibody is reactive with Human, Mouse and Rat samples.

Quick Overview for DCT antibody (AA 24-519) (Fluoro488) (ABIN7986209)

Target: DCT (Dopachrome Tautomerase (DCT))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This DCT antibody is conjugated to Fluoro488

Application: Flow Cytometry (FACS)

Product Details anti-DCT Antibody (Fluoro488)

Binding Specificity: AA 24-519

Purpose: Anti-TRP2/DCT Antibody Fluoro488 Conjugated

Cross-Reactivity (Details): No cross-reactivity with other proteins.

Purification: Immunogen affinity purified.

Immunogen: E.coli-derived human TRP2/DCT recombinant protein (Position: Q24-A519).

Isotype: IgG

Application Details

Application Notes: Flow Cytometry, Optimal dilutions should be determined by end users.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

Expiry Date: 12 months

Target Details for DCT

Target: DCT (Dopachrome Tautomerase (DCT))

Alternative Name: DCT

Background:

Background: Dopachrome tautomerase (dopachrome delta-isomerase, tyrosine-related protein 2), also known as DCT, is a human gene. The TYR-related proteins, TRP1 and TRP2, are also specifically expressed in melanocytes, and they likewise contribute to the synthesis of melanin within the melanosomes. The TRPs, including TYR, all share a similar transmembrane region, contain two metal-binding regions and a cysteinerich epidermal growth factor motif, and are localized in the melanosomal membrane. These proteins, however, have distinct catalytic activity, and they individually contribute to the biosynthesis of melanin biopolymers. The TRPs are believed to exist as a multi-enzyme complex, as these proteins form aggregates together, and the expression of TRP1 also helps stabilize TYR in melanocytes.

Gene Full Name: dopachrome tautomerase

Gene ID: 1638

UniProt: P40126