DMRT1 antibody (N-Term) (APC)

Catalog No. ABIN7986314

The APC-conjugated Rabbit Polyclonal anti-DMRT1 antibody (ABIN7986314) specifically detects DMRT1 in FACS. The antibody is reactive with Human, Mouse and Rat samples.

Quick Overview for DMRT1 antibody (N-Term) (APC) (ABIN7986314)

Target: DMRT1 (Doublesex and Mab-3 Related Transcription Factor 1 (DMRT1))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This DMRT1 antibody is conjugated to APC

Application: Flow Cytometry (FACS)

Product Details anti-DMRT1 Antibody (APC)

Binding Specificity: N-Term

Purpose: Anti-DMRT1 Antibody APC Conjugated

Specificity: No cross reactivity with other proteins.

Cross-Reactivity (Details): No cross-reactivity with other proteins

Predicted Reactivity: different from the related mouse sequence by one amino acid.

Purification: Immunogen affinity purified.

Immunogen: A synthetic peptide corresponding to a sequence at the N-terminus of human DMRT1, different from the related mouse sequence by one amino acid.

Isotype: IgG

Application Details

Application Notes: Flow Cytometry, Optimal dilutions should be determined by end users.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

Expiry Date: 12 months

Target Details for DMRT1

Target: DMRT1 (Doublesex and Mab-3 Related Transcription Factor 1 (DMRT1))

Alternative Name: DMRT1

Background:

Background: Doublesex and mab-3 related transcription factor 1, also known as DMRT1, is a protein which in humans is encoded by the DMRT1 gene. This gene is found in a cluster with two other members of the gene family, having in common a zinc finger-like DNA-binding motif (DM domain). The DM domain is an ancient, conserved component of the vertebrate sex-determining pathway that is also a key regulator of male development in flies and nematodes. This gene exhibits a gonad-specific and sexually dimorphic expression pattern. Defective testicular development and XY feminization occur when this gene is hemizygous.

Gene Full Name: doublesex and mab-3 related transcription factor 1

Sequence Similarities: Belongs to the DMRT family.

Gene ID: 1761

UniProt: Q9Y5R6