DUSP1 antibody (N-Term) (FITC)

Catalog No. ABIN7986448

The Rabbit Polyclonal anti-DUSP1 antibody is suitable to detect DUSP1 in samples from Human. It has been validated for FACS.

Quick Overview for DUSP1 antibody (N-Term) (FITC) (ABIN7986448)

Target: DUSP1 (Dual Specificity Phosphatase 1 (DUSP1))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This DUSP1 antibody is conjugated to FITC

Application: Flow Cytometry (FACS)

Product Details anti-DUSP1 Antibody (FITC)

Binding Specificity: N-Term

Purpose: Anti-MKP-1/DUSP1 Antibody FITC Conjugated

Cross-Reactivity (Details): No cross-reactivity with other proteins.

Purification: Immunogen affinity purified.

Immunogen: A synthetic peptide corresponding to a sequence at the N-terminus of human MKP-1/DUSP1, which shares 96.3% amino acid (aa) sequence identity with both mouse and rat MKP-1/DUSP1.

Isotype: IgG

Application Details

Application Notes: Flow Cytometry, Optimal dilutions should be determined by end users.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

Expiry Date: 12 months

Target Details for DUSP1

Target: DUSP1 (Dual Specificity Phosphatase 1 (DUSP1))

Alternative Name: DUSP1

Background:

Background: Dual specificity protein phosphatase 1 is an enzyme that in humans is encoded by the DUSP1 gene. The protein encoded by this gene is a phosphatase with dual specificity for tyrosine and threonine. The encoded protein can dephosphorylate MAP kinase MAPK1/ERK2, which results in its involvement in several cellular processes. This protein appears to play an important role in the human cellular response to environmental stress as well as in the negative regulation of cellular proliferation. Finally, the encoded protein can make some solid tumors resistant to both chemotherapy and radiotherapy, making it a target for cancer therapy.

Gene Full Name: dual specificity phosphatase 1

Gene ID: 1843

UniProt: P28562