DUSP2 antibody (AA 1-250) (APC)

Catalog No. ABIN7986462

This Rabbit Polyclonal antibody specifically detects DUSP2 in FACS. It exhibits reactivity toward Human, Mouse and Rat.

Quick Overview for DUSP2 antibody (AA 1-250) (APC) (ABIN7986462)

Target: DUSP2 (Dual Specificity Phosphatase 2 (DUSP2))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This DUSP2 antibody is conjugated to APC

Application: Flow Cytometry (FACS)

Product Details anti-DUSP2 Antibody (APC)

Binding Specificity: AA 1-250

Purpose: Anti-DUSP2 Antibody APC Conjugated

Cross-Reactivity (Details): No cross-reactivity with other proteins

Predicted Reactivity: Human DUSP2 shares 85.6% amino acid (aa) sequence identity with mouse DUSP2.

Purification: Immunogen affinity purified.

Immunogen: E.coli-derived human DUSP2 recombinant protein (Position: M1-G250). Human DUSP2 shares 85.6% amino acid (aa) sequence identity with mouse DUSP2.

Isotype: IgG

Application Details

Application Notes: Flow Cytometry, Optimal dilutions should be determined by end users.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

Expiry Date: 12 months

Target Details for DUSP2

Target: DUSP2 (Dual Specificity Phosphatase 2 (DUSP2))

Alternative Name: DUSP2

Background:

Background: The protein encoded by this gene is a member of the dual specificity protein phosphatase subfamily. These phosphatases inactivate their target kinases by dephosphorylating both the phosphoserine/threonine and phosphotyrosine residues. They negatively regulate members of the mitogen-activated protein (MAP) kinase superfamily (MAPK/ERK, SAPK/JNK, p38), which are associated with cellular proliferation and differentiation. Different members of the family of dual specificity phosphatases show distinct substrate specificities for various MAP kinases, different tissue distribution and subcellular localization, and different modes of inducibility of their expression by extracellular stimuli. This gene product inactivates ERK1 and ERK2, is predominantly expressed in hematopoietic tissues, and is localized in the nucleus.

Gene Full Name: dual specificity phosphatase 2

Gene ID: 1844

UniProt: Q05923